Karen Gauvain, M.D.  gauvain_k@kids.wustl.edu

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Assistant Professor Pediatrics, Divsion of Pediatric Hematology/Oncology
Researcher, Patient Oriented Research Unit
Hematology and Oncology

phone: (314) 454-6018

Research Interests

My current research focus is specifically on angiogenesis and vascular function in pediatric brain tumors. I have a background in both PET and MR imaging research prior to and during medical school, as well as a resident, fellow and faculty member. My specific research interests include clinical trials in brain tumor patients, specifically with biologic agents and incorporation of biologic studies in order to better understand and improve the outcome of these poor prognosis dieases. My additional interest is in incorporating advancing imaging technology to assess response, early relapse, and late effects in patients with brain tumors.


  • BS, University of Missouri1989
  • MD, Distinction in Research, Saint Louis University1998
  • MSPH, St. Louis University2013


  • Pediatric Resident, St. Louis Children's Hospital1998 - 2001
  • Fellow, Washington University School of Medicine2001 - 2004

Licensure and Board Certification

  • 2001 - PresPediatrics
  • 2004 - PresMO, Missouri State Board of Registration for the Healing Arts
  • 2006 - PresPediatric Hematology/Oncology

Honors and Awards

  • NIH Pediatric Research Loan Repayment Program2003 - 2005
  • Guardian of Childhood Winner2016

Selected Publications view all (15)

Publication Co-Authors

Presence of cerebral microbleeds is associated with worse executive function in pediatric brain tumor survivors. Neuro-Oncology. 2016;18(11):1548-1558. PMID:27540084 
Grade II pilocytic astrocytoma in a 3-month-old patient with encephalocraniocutaneous lipomatosis (ECCL): case report and literature review of low grade gliomas in ECCL. Am J Med Genet A. 2015. doi:10.1002/ajmg.a.37017  PMID:25705862 
Evaluation of Physician and Nurse Dyad Training Procedures to Deliver a Palliative and End-of-Life Communication Intervention to Parents of Children with a Brain Tumor. J Pediatr Oncol Nurs. 2015. doi:10.1177/1043454214563410  PMID:25623029 
Outcomes of pediatric low-grade gliomas treated with radiation therapy: a single-institution study. J Pediatr Hematol Oncol. 2014. doi:10.1097/MPH.0000000000000142  PMID:24714505 
Rapidly progressive primary leptomeningeal atypical teratoid/rhabdoid tumor: a report of 2 cases. J Child Neurol. 2012;27(12):1597-601. doi:10.1177/0883073812436878  PMID:22378667 
MRI detection of early bone metastases in b16 mouse melanoma models. Clin Exp Metastasis. 2005;22(5):403-11. doi:10.1007/s10585-005-1264-9  PMCID:PMC2726655  PMID:16283483 
Evaluating pediatric brain tumor cellularity with diffusion-tensor imaging. AJR Am J Roentgenol. 2001;177(2):449-54. doi:10.2214/ajr.177.2.1770449  PMID:11461881 
Measurement of regional pulmonary blood flow with PET. J Nucl Med. 1995;36(3):371-7. PMID:7884497 
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