Karen Gauvain, M.D.  gauvain_k@kids.wustl.edu

Assistant Professor Pediatrics, Divsion of Pediatric Hematology/Oncology
Researcher, Patient Oriented Research Unit
Patient Oriented Research UnitHematology and Oncology

phone: (314) 454-6018

Research Interests

My current research focus is specifically on angiogenesis and vascular function in pediatric brain tumors. I have a background in both PET and MR imaging research prior to and during medical school, as well as a resident, fellow and faculty member. My specific research interests include clinical trials in brain tumor patients, specifically with biologic agents and incorporation of biologic studies in order to better understand and improve the outcome of these poor prognosis dieases. My additional interest is in incorporating advancing imaging technology to assess response, early relapse, and late effects in patients with brain tumors.

Education

  • BS, University of Missouri1989
  • MD, Distinction in Research, Saint Louis University1998
  • MSPH, St. Louis University2013

Training

  • Pediatric Resident, St. Louis Children's Hospital1998 - 2001
  • Fellow, Washington University School of Medicine2001 - 2004

Licensure and Board Certification

  • Pediatrics 2001
  • MO, Missouri State Board of Registration for the Healing Arts 2004
  • Pediatric Hematology/Oncology 2006

Honors

  • NIH Pediatric Research Loan Repayment Program2003 - 2005
  • Guardian of Childhood Winner2016

Selected Publications view all (14)


1.
Presence of cerebral microbleeds is associated with worse executive function in pediatric brain tumor survivors. Neuro-Oncology. 2016;18(11):1548-1558. PMID:27540084 
2.
Resolution of precocious puberty following resection of fourth ventricular medulloblastoma: case report JNS Pediatrics. 2015. 
3.
Grade II pilocytic astrocytoma in a 3-month-old patient with encephalocraniocutaneous lipomatosis (ECCL): case report and literature review of low grade gliomas in ECCL. Am J Med Genet A. 2015. doi:10.1002/ajmg.a.37017  PMID:25705862 
4.
Evaluation of Physician and Nurse Dyad Training Procedures to Deliver a Palliative and End-of-Life Communication Intervention to Parents of Children with a Brain Tumor. J Pediatr Oncol Nurs. 2015. doi:10.1177/1043454214563410  PMID:25623029 
5.
Outcomes of pediatric low-grade gliomas treated with radiation therapy: a single-institution study. J Pediatr Hematol Oncol. 2014. doi:10.1097/MPH.0000000000000142  PMID:24714505 
6.
Rapidly progressive primary leptomeningeal atypical teratoid/rhabdoid tumor: a report of 2 cases. J Child Neurol. 2012;27(12):1597-601. doi:10.1177/0883073812436878  PMID:22378667 
7.
MRI detection of early bone metastases in b16 mouse melanoma models. Clin Exp Metastasis. 2005;22(5):403-11. doi:10.1007/s10585-005-1264-9  PMCID:PMC2726655  PMID:16283483 
8.
Evaluating pediatric brain tumor cellularity with diffusion-tensor imaging. AJR Am J Roentgenol. 2001;177(2):449-54. doi:10.2214/ajr.177.2.1770449  PMID:11461881 
9.
Measurement of regional pulmonary blood flow with PET. J Nucl Med. 1995;36(3):371-7. PMID:7884497 
10.
An 8-year old girl with a supratentorial mass Brain Pathology. 
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