Cliff J. Luke, Ph.D.

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Associate Professor of Pediatrics, Newborn Medicine
Newborn Medicine

phone: (314) 454-6148


  • BSc, Hons II(i), University of Liverpool1994
  • PhD, University of Surrey1998


  • Postodoctoral Fellow, The Children's Hospital1998 - 2001
  • Research fellow in Pediatrics, Harvard Medical School1998 - 2001
  • Research Associate, The Children's Hospital2001 - 2004

Honors and Awards

  • Aaron Janoff Recipient of the Young Investigator Award2001

Selected Publications view all (37)

SERPINB12 Is a Slow-Binding Inhibitor of Granzyme A and Hepsin. Biochemistry. 2015;54(45):6756-9. PMCID:PMC4900762  PMID:26497600 
A pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegans. PLoS One. 2012;7(7):e40145. PMCID:PMC3388072  PMID:22768338 
An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury. Cell. 2007;130(6):1108-19. PMCID:PMC2128786  PMID:17889653 
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