Aimée Baumann-Dudenhoeffer, M.D.  Moore_A@kids.wustl.edu

Instructor in Pediatrics, Newborn Medicine
Newborn MedicinePediatric Research

phone: (314) 454-6148

Research Interests

Antibiotic resistance is a growing threat to human health. Bacteria that live in the human gut are an important reservoir of antibiotic resistance genes, and can potentially exchange those resistance genes with pathogens that cause human disease. Why some human gut-associated microbial communities harbor clinically important antibiotic resistance genes but others do not is poorly understood. Because infancy and early childhood represent critical periods for the development of the microbial community in the human gut, we hypothesize that this is also a critical time for antibiotic resistance genes to be established in human gut-associated microbial communities. In the laboratory of Gautam Dantas, Ph.D. (http://dantaslab.wustl.edu/index.html), I am currently studying the impact of various early childhood exposures on the developing cohort of antibiotic resistance genes in host-associated microbial communities.

Education

  • BA, Cornell University2000
  • MD, Washington University in St. Louis School of Medicine2005

Training

  • Pediatric Residency, Albert Einstein College of Medicine-- Jacobi Medical Center2005 - 2008
  • Neonatal-Perinatal Medicine Fellowship, Washington University in St Louis School of Medicine2009 - 2012

Licensure and Board Certification

  • MO, Missouri Medical License
  • Board Certified in Pediatrics 2009
  • Neonatal-Perinatal Medicine 2014

Selected Publications view all (9)


Publication Co-Authors

1.
Gut Resistome Development in Healthy Twin Pairs in the First Year of Life Microbiome. 2015;3(29). doi:10.1186/s40168-015-0095-4  PMCID:PMC4511998  
2.
The neurodevelopmental impact of neonatal morphine administration. Brain Sci. 2014;4(2):321-34. doi:10.3390/brainsci4020321  PMID:24961764 
3.
Optimizing Temperature During Resuscitation Neoreviews. 2013;14(6):329. 
4.
Pediatric fecal microbiota harbor diverse and novel antibiotic resistance genes. PLoS One. 2013;8(11):e78822. doi:10.1371/journal.pone.0078822  PMCID:PMC3827270  PMID:24236055 
5.
Index of Suspicion in the Nursery Case 1: Subcostal Retractions After Shoulder Dystocia in a Term Infant Case 2: Cleft Palate in a Neonate Neoreviews. 2012;13(8):e491-e493. 
6.
Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. Proc Natl Acad Sci U S A. 2011;108(15):6252-7. doi:10.1073/pnas.1102938108  PMCID:PMC3076821  PMID:21436049 
7.
Functional metagenomic investigations of the human intestinal microbiota. Front Microbiol. 2011;2:188. doi:10.3389/fmicb.2011.00188  PMCID:PMC3195301  PMID:22022321 
8.
The Stroke Trials Directory: An Online Registry of Clinical Trials in Cerebrovascular Disease Semin Cerebrovasc Dis Stroke. 2003;3(1):48-53. 
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