Laura Schuettpelz, M.D, Ph.D.  schuettpelz_l@kids.wustl.edu

Assistant Professor of Pediatrics, Hematology and Oncology
Developmental BiologyHematology and Oncology

phone: 314-286-1813

Education

  • B.S., Summa Cum Laude, Creighton University1995
  • Ph.D., Northwestern University2000
  • M.D., Northwestern University2005

Training

  • Residency in Pediatrics, Washington Univeristy School of Medicine2005 - 2008
  • Fellowship in Pediatric Hematology/Oncology, Washington University School of Medicine2008 - 2011

Licensure and Board Certification

  • MO, Missouri Medical License2005
  • General Pediatrics2009
  • Pediatric Hematology/Oncology2013

Honors

  • David Gilstrap Award2008
  • James P.Keating Oustanding Resident Award2008
  • Outstanding Fellow Teaching Award2009
  • Scholar of the Child Health Research Center of Excellence in Developmental Biology2012 - Pres
  • Faculty Scholar Award, Children's Discovery Institute of Washington University2013 - Pres

Selected Publications view all (10)


Publication Co-Authors

  1. Schuettpelz LG, Borgerding JN, Christopher MJ, Gopalan PK, Romine MP, Herman AC, Woloszynek JR, Greenbaum AM, Link DC. G-CSF regulates hematopoietic stem cell activity, in part, through activation of Toll-like receptor signaling. Leukemia. 2014;28(9):1851-60. doi:10.1038/leu.2014.68  PMCID:PMC4130805  PMID:24518205  
  2. Greenbaum A, Hsu YM, Day RB, Schuettpelz LG, Christopher MJ, Borgerding JN, Nagasawa T, Link DC. CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature. 2013;495(7440):227-30. doi:10.1038/nature11926  PMCID:PMC3600148  PMID:23434756  
  3. Schuettpelz LG, Link DC. Regulation of hematopoietic stem cell activity by inflammation. Front Immunol. 2013;4:204. doi:10.3389/fimmu.2013.00204  PMCID:PMC3715736  PMID:23882270  
  4. Schuettpelz LG, Gopalan PK, Giuste FO, Romine MP, van Os R, Link DC. Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function. Blood. 2012;120(15):2981-9. doi:10.1182/blood-2012-02-409839  PMCID:PMC3471512  PMID:22936656  
  5. Link DC, Schuettpelz LG, Shen D, Wang J, Walter MJ, Kulkarni S, Payton JE, Ivanovich J, Goodfellow PJ, Le Beau M, Koboldt DC, Dooling DJ, Fulton RS, Bender RH, Fulton LL, Delehaunty KD, Fronick CC, Appelbaum EL, Schmidt H, Abbott R, O'Laughlin M, Chen K, McLellan MD, Varghese N, Nagarajan R, Heath S, Graubert TA, Ding L, Ley TJ, Zambetti GP, Wilson RK, Mardis ER. Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. JAMA. 2011;305(15):1568-76. doi:10.1001/jama.2011.473  PMCID:PMC3170052  PMID:21505135  
  6. Schuettpelz LG, Link DC. Niche competition and cancer metastasis to bone. J Clin Invest. 2011;121(4):1253-5. doi:10.1172/JCI57229  PMCID:PMC3069798  PMID:21436576  
  7. Schuettpelz LG, McDonald S, Whitesell K, Desruisseau DM, Grange DK, Gurnett CA, Wilson DB. Pilocytic astrocytoma in a child with Noonan syndrome. Pediatr Blood Cancer. 2009;53(6):1147-9. doi:10.1002/pbc.22193  PMID:19621452  
  8. Schuettpelz LG, Behrens D, Goldsmith MI, Druley TE. Severe ceftriaxone-induced hemolysis complicated by diffuse cerebral ischemia in a child with sickle cell disease. J Pediatr Hematol Oncol. 2009;31(11):870-2. doi:10.1097/MPH.0b013e3181b7eda2  PMID:19829151  
  9. Meng Y, Graves L, Do TV, So J, Fishman DA. Upregulation of FasL by LPA on ovarian cancer cell surface leads to apoptosis of activated lymphocytes. Gynecol Oncol. 2004;95(3):488-95. doi:10.1016/j.ygyno.2004.07.052  PMID:15581951  
  10. Graves LE, Ariztia EV, Navari JR, Matzel HJ, Stack MS, Fishman DA. Proinvasive properties of ovarian cancer ascites-derived membrane vesicles. Cancer Res. 2004;64(19):7045-9. doi:10.1158/0008-5472.CAN-04-1800  PMID:15466198