Pediatric Research

Jennifer N. Avari Silva, M.D. silva_j@kids.wustl.edu

Assistant Professor of Pediatrics, Cardiology

Patient Oriented Research Unit Cardiology

phone: (314) 454-6095

Education

BA, Union College, 1997
MD, St. George's University School of Medicine, 2002

Training

Residency in Pediatrics, Miami Children's Hospital, 2002 - 2005
Fellowship in Pediatric Cardiology, Washington University School of Medicine/St. Louis Children's Hospital, 2005 - 2008
4th year Advanced Fellowshipin Pediatric and Adult Congenital Electrophysiology, Children's Hospital Boston/Harvard Medical School, 2008 - 2009

Licensure and Board Certification

ECFMG , 2002
Missouri Board of Medicine , 2005
Diplomate, American Board of Pediatrics , 2005
Missouri Board of Medicine , 2009
IL, Department of Financial and Professional Regulation Divisional of Professional Regulation , 2011
MO, DEA , 2012
MO, BNDD , 2012
American Board of Pediatrics, Subboard of Pediatric Cardiology , 2012
MO, Missouri State Board of Registration for the Healing Arts , 2013
International Board of Heart Rhythm Examiners, Certified Electrophysiology Specialist--Pediatric Cardiology, certificate #: 192745 , 2015

Honors

Fellow, Heart Rhythm Society, 2016 - Pres

Selected Publications view all (32)

Publication Co-Authors

Marwan Shinawi, M.D.

Philip Levy, M.D.

Charles Canter, M.D.

George F. Van Hare, M.D.

David Balzer, M.D.

Avihu Z. Gazit, M.D.

Francis Sessions Cole, III, M.D.

1.	Rudokas MW, Patel MD, Bowman TM, Van Hare GF, Silva JNAS. Lead Advancement in Pediatric Patients with SelectSecure 3830 Pacing Leads Journal of Cardiology and Current Research. 2014.
2.	Silva JN, Erickson CC, Carter CD, Greene EA, Kantoch M, Collins KK, Miyake CY, Carboni MP, Rhee EK, Papez A, Anand V, Bowman TM, Van Hare GF, Participating Members of Pediatric and Congenital Electrophysiology Society (PACES). Management of pediatric tachyarrhythmias on mechanical support. Circ Arrhythm Electrophysiol. 2014. doi:10.1161/CIRCEP.113.000973 PMID:24987047
3.	Moore JP, Patel PA, Shannon KM, Albers EL, Salerno JC, Stein MA, Stephenson EA, Mohan S, Shah MJ, Asakai H, Pflaumer A, Czosek RJ, Everitt MD, Garnreiter JM, McCanta AC, Papez AL, Escudero C, Sanatani S, Cain NB, Kannankeril PJ, Bratincsak A, Mandapati R, Silva JN, Knecht KR, Balaji S. Predictors of myocardial recovery in pediatric tachycardia-induced cardiomyopathy. Heart Rhythm. 2014;11(7):1163-9. doi:10.1016/j.hrthm.2014.04.023 PMID:24751393
4.	Silva JN, VON Bergen NH, Dubin AM, Collins KK, Chen J, Bowman TM, Van Hare GF. Assessment of intrathoracic impedance algorithm in the pediatric and adult congenital population. Pacing Clin Electrophysiol. 2014. doi:10.1111/pace.12372 PMID:24646399
5.	Mills KI, Anderson J, Levy PT, Cole FS, Silva JN, Kulkarni S, Shinawi M. Duplication of 20p12.3 associated with familial Wolff-Parkinson-White syndrome. Am J Med Genet A. 2013;161A(1):137-44. doi:10.1002/ajmg.a.35701 PMID:23239491
6.	Silva JN, Silva JR. Updates on the inherited cardiac ion channelopathies: from cell to clinical. Curr Treat Options Cardiovasc Med. 2012;14(5):473-89. doi:10.1007/s11936-012-0198-1 PMID:22865245
7.	Silva JN, Vashist S, Van Hare GF. 3:2 antegrade atrioventricular block with AV nodal reentrant tachycardia: what is the mechanism and where is the block? Pacing Clin Electrophysiol. 2012;35(7):877-9. doi:10.1111/j.1540-8159.2012.03420.x PMID:22553974
8.	Vashist S, Silva JN, Van Hare GF, Papez AL, Su WW, Rhee EK. Unusually high association of hypertrophic cardiomyopathy and complex heart defects in children with fasciculoventricular pathways. Pacing Clin Electrophysiol. 2012;35(3):308-13. doi:10.1111/j.1540-8159.2011.03274.x PMID:22242628
9.	Ghosh S, Silva JN, Canham RM, Bowman TM, Zhang J, Rhee EK, Woodard PK, Rudy Y. Electrophysiologic substrate and intraventricular left ventricular dyssynchrony in nonischemic heart failure patients undergoing cardiac resynchronization therapy. Heart Rhythm. 2011;8(5):692-9. doi:10.1016/j.hrthm.2011.01.017 PMCID:PMC3096066 PMID:21232630
10.	Silva JN, Canter CE, Singh TP, Gauvreau K, Piercey GE, Berul CI, Smoot LB, Blume ED, Fynn-Thompson F, Almond CS. Outcomes of heart transplantation using donor hearts from infants with sudden infant death syndrome. J Heart Lung Transplant. 2010;29(11):1226-30. doi:10.1016/j.healun.2010.06.004 PMID:20691612

1.	Moore JP, Wang S, Albers EL, Salerno JC, Stephenson EA, Shah MJ, Pflaumer A, Czosek RJ, Garnreiter JM, Collins K, Papez AL, Sanatani S, Cain NB, Kannankeril PJ, Perry JC, Mandapati R, Silva JN, Balaji S, Shannon KM. A Clinical Risk Score to Improve the Diagnosis of Tachycardia-Induced Cardiomyopathy in Childhood. Am J Cardiol. 2016;118(7):1074-80. PMID:27515893
2.	Nguyen HH, Shahanavaz S, Van Hare GF, Balzer DT, Nicolas R, Avari SIlva JN. Percutaneous Pulmonary Valve Implantation Alters Electrophysiologic Substrate J Am Heart Assoc. 2016;5(10). doi:10.1161/JAHA.116.004325 PMCID:PMC5121524 PMID:27694326
3.	Avari Silva JN, Bromberg BI, Emge FK, Bowman TM, Van Hare GF. Implantable Loop Recorder Monitoring for Refining Management of Children With Inherited Arrhythmia Syndromes. J Am Heart Assoc. 2016;5(6). PMCID:PMC4937287 PMID:27231019
4.	Dykes JC, Al-mousily MF, Abuchaibe EC, Silva JN, Zadinsky J, Duarte D, Welch E. The incidence of chromosome abnormalities in neonates with structural heart disease Heart. 2016;102(8):634-7. doi:10.1136/heartjnl-2015-308650 PMID:26843533
5.	Nguyen HH, Van Hare GF, Rudokas M, Bowman T, Silva JN. SPEAR Trial: Smartphone Pediatric ElectrocARdiogram Trial. PLoS One. 2015;10(8):e0136256. PMCID:PMC4546652 PMID:26295569
6.	Rockefeller TA, Silva JNA, Liao S, Vichharajani A. . Corrected QT prolongation and bradycardia during therapeutic hypothermia in an infant: a case report NoeReviews. 2015.
7.	Zhang J, Sacher F, Hoffmayer K, O'Hara T, Strom M, Cuculich P, Silva J, Cooper D, Faddis M, Hocini M, Haïssaguerre M, Scheinman M, Rudy Y. Cardiac electrophysiological substrate underlying the ECG phenotype and electrogram abnormalities in Brugada syndrome patients. Circulation. 2015;131(22):1950-9. PMCID:PMC4452400 PMID:25810336
8.	Vijayakumar R, Silva JNA, Desouza KA, Abraham RL, Strom M, Sacher F, Van Hare GF, Haïssaguerre M, Roden DM, Rudy Y. Electrophysiologic substrate in congenital Long QT syndrome: noninvasive mapping with electrocardiographic imaging (ECGI). Circulation. 2014;130(22):1936-1943. PMCID:PMC4245321 PMID:25294783
9.	Rudokas MW, Patel MD, Bowman TM, Van Hare GF, Silva JNAS. Lead Advancement in Pediatric Patients with SelectSecure 3830 Pacing Leads Journal of Cardiology and Current Research. 2014.
10.	Silva JN, Erickson CC, Carter CD, Greene EA, Kantoch M, Collins KK, Miyake CY, Carboni MP, Rhee EK, Papez A, Anand V, Bowman TM, Van Hare GF, Participating Members of Pediatric and Congenital Electrophysiology Society (PACES). Management of pediatric tachyarrhythmias on mechanical support. Circ Arrhythm Electrophysiol. 2014. doi:10.1161/CIRCEP.113.000973 PMID:24987047
11.	Moore JP, Patel PA, Shannon KM, Albers EL, Salerno JC, Stein MA, Stephenson EA, Mohan S, Shah MJ, Asakai H, Pflaumer A, Czosek RJ, Everitt MD, Garnreiter JM, McCanta AC, Papez AL, Escudero C, Sanatani S, Cain NB, Kannankeril PJ, Bratincsak A, Mandapati R, Silva JN, Knecht KR, Balaji S. Predictors of myocardial recovery in pediatric tachycardia-induced cardiomyopathy. Heart Rhythm. 2014;11(7):1163-9. doi:10.1016/j.hrthm.2014.04.023 PMID:24751393
12.	Silva JN, VON Bergen NH, Dubin AM, Collins KK, Chen J, Bowman TM, Van Hare GF. Assessment of intrathoracic impedance algorithm in the pediatric and adult congenital population. Pacing Clin Electrophysiol. 2014. doi:10.1111/pace.12372 PMID:24646399
13.	Mills KI, Anderson J, Levy PT, Cole FS, Silva JN, Kulkarni S, Shinawi M. Duplication of 20p12.3 associated with familial Wolff-Parkinson-White syndrome. Am J Med Genet A. 2013;161A(1):137-44. doi:10.1002/ajmg.a.35701 PMID:23239491
14.	Silva JN, Silva JR. Updates on the inherited cardiac ion channelopathies: from cell to clinical. Curr Treat Options Cardiovasc Med. 2012;14(5):473-89. doi:10.1007/s11936-012-0198-1 PMID:22865245
15.	Silva JN, Vashist S, Van Hare GF. 3:2 antegrade atrioventricular block with AV nodal reentrant tachycardia: what is the mechanism and where is the block? Pacing Clin Electrophysiol. 2012;35(7):877-9. doi:10.1111/j.1540-8159.2012.03420.x PMID:22553974
16.	Vashist S, Silva JN, Van Hare GF, Papez AL, Su WW, Rhee EK. Unusually high association of hypertrophic cardiomyopathy and complex heart defects in children with fasciculoventricular pathways. Pacing Clin Electrophysiol. 2012;35(3):308-13. doi:10.1111/j.1540-8159.2011.03274.x PMID:22242628
17.	Ghosh S, Silva JN, Canham RM, Bowman TM, Zhang J, Rhee EK, Woodard PK, Rudy Y. Electrophysiologic substrate and intraventricular left ventricular dyssynchrony in nonischemic heart failure patients undergoing cardiac resynchronization therapy. Heart Rhythm. 2011;8(5):692-9. doi:10.1016/j.hrthm.2011.01.017 PMCID:PMC3096066 PMID:21232630
18.	Silva JN, Canter CE, Singh TP, Gauvreau K, Piercey GE, Berul CI, Smoot LB, Blume ED, Fynn-Thompson F, Almond CS. Outcomes of heart transplantation using donor hearts from infants with sudden infant death syndrome. J Heart Lung Transplant. 2010;29(11):1226-30. doi:10.1016/j.healun.2010.06.004 PMID:20691612
19.	Collins KK, Silva JN, Rhee EK, Schaffer MS. Use of a wearable automated defibrillator in children compared to young adults. Pacing Clin Electrophysiol. 2010;33(9):1119-24. doi:10.1111/j.1540-8159.2010.02819.x PMID:20561227
20.	Silver ES, Silva JN, Ceresnak SR, Chiesa NA, Rhee EK, Dubin AM, Avasarala K, Van Hare GF, Collins KK. Cryoablation with an 8-mm tip catheter for pediatric atrioventricular nodal reentrant tachycardia is safe and efficacious with a low incidence of recurrence. Pacing Clin Electrophysiol. 2010;33(6):681-6. doi:10.1111/j.1540-8159.2010.02706.x PMID:20230479
21.	Silva JN, Canter CE. Current management of pediatric dilated cardiomyopathy. Curr Opin Cardiol. 2010;25(2):80-7. doi:10.1097/HCO.0b013e328335b220 PMID:20019605
22.	Silva JN, Van Hare G. Management of postoperative pediatric cardiac arrhythmias: current state of the art. Curr Treat Options Cardiovasc Med. 2009;11(5):410-6. PMID:19846040
23.	Collins KK, Van Hare GF, Kertesz NJ, Law IH, Bar-Cohen Y, Dubin AM, Etheridge SP, Berul CI, Avari JN, Tuzcu V, Sreeram N, Schaffer MS, Fournier A, Sanatani S, Snyder CS, Smith RT Jr, Arabia L, Hamilton R, Chun T, Liberman L, Kakavand B, Paul T, Tanel RE. Pediatric nonpost-operative junctional ectopic tachycardia medical management and interventional therapies. J Am Coll Cardiol. 2009;53(8):690-7. doi:10.1016/j.jacc.2008.11.019 PMID:19232902
24.	Ghosh S, Avari JN, Rhee EK, Woodard PK, Rudy Y. Hypertrophic cardiomyopathy with preexcitation: insights from noninvasive electrocardiographic imaging (ECGI) and catheter mapping. J Cardiovasc Electrophysiol. 2008;19(11):1215-7. doi:10.1111/j.1540-8167.2008.01203.x PMCID:PMC2631093 PMID:18479334
25.	Avari JN, Rhee EK. Cardiac resynchronization therapy for pediatric heart failure. Heart Rhythm. 2008;5(10):1476-8. doi:10.1016/j.hrthm.2008.05.024 PMID:18672406
26.	Ghosh S, Rhee EK, Avari JN, Woodard PK, Rudy Y. Cardiac memory in patients with Wolff-Parkinson-White syndrome: noninvasive imaging of activation and repolarization before and after catheter ablation. Circulation. 2008;118(9):907-15. doi:10.1161/CIRCULATIONAHA.108.781658 PMCID:PMC2747627 PMID:18697818
27.	Avari JN, Rhee EK. Markers of coronary sinus accessory pathways in pediatrics. Pacing Clin Electrophysiol. 2008;31(8):968-73. doi:10.1111/j.1540-8159.2008.01123.x PMID:18684252
28.	Ghosh S, Avari JN, Rhee EK, Woodard PK, Rudy Y. Noninvasive electrocardiographic imaging (ECGI) of epicardial activation before and after catheter ablation of the accessory pathway in a patient with Ebstein anomaly. Heart Rhythm. 2008;5(6):857-60. doi:10.1016/j.hrthm.2008.03.011 PMCID:PMC2967218 PMID:18482872
29.	Avari JN, Jay KS, Rhee EK. Experience and results during transition from radiofrequency ablation to cryoablation for treatment of pediatric atrioventricular nodal reentrant tachycardia. Pacing Clin Electrophysiol. 2008;31(4):454-60. doi:10.1111/j.1540-8159.2008.01033.x PMID:18373764
30.	Ghosh S, Avari JN, Rhee EK, Woodard PK, Rudy Y. Noninvasive electrocardiographic imaging (ECGI) of a univentricular heart with Wolff-Parkinson-White syndrome. Heart Rhythm. 2008;5(4):605-8. doi:10.1016/j.hrthm.2007.12.018 PMCID:PMC2329801 PMID:18325851
31.	Gazit AZ, Avari JN, Balzer DT, Rhee EK. Electrocardiographic diagnosis of myocardial ischemia in children: is a diagnostic electrocardiogram always diagnostic? Pediatrics. 2007;120(2):440-4. doi:10.1542/peds.2007-0170 PMID:17671071
32.	Lehman GC, Van Hare GF, Silva JNA. . Atrial Tachycardia in an Electrically Dissociated Native Right Atrium after Heart Transplantation. Heart Rhythm Case Reports.