Jennifer A Wambach, M.D.

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Assistant Professor of Pediatrics, Newborn Medicine
Researcher, Pathobiology
Newborn Medicine

phone: (314) 454-6148

Research Interests

Genetic Mechanisms Underlying Neonatal Respiratory Distress Syndrome


  • BS, Vanderbilt University1997
  • MD, Vanderbilt University School of Medicine2001
  • MS, Washington University School of Medicine2010


  • Resident, Pediatrics, Northwestern University School of Medicine2001 - 2004
  • Chief Resident, Pediatrics, Northwestern University School of Medicine2004 - 2005
  • Fellow, Newborn Medicine, Washington University School of Medicine2005 - 2008

Licensure and Board Certification

  • 2004 - PresAmerican Board of Pediatrics, General Pediatrics
  • 2010 - PresAmerican Board of Pediatrics, Neonatal-Perinatal Medicine


  • Phi Beta Kappa, Vanderbilt University1997
  • Amos Christie Scholar in Pediatrics, Vanderbilt University School of Medicine1998
  • Microbes and Defense Academic Honor Society, Vanderbilt University School of Medicine1998
  • Dean's Award, Vanderbilt University School of Medicine2001
  • Resident Teaching Award, Northwestern University School of Medicine2002
  • National Institutes of Health, Loan Repayment Program2007 - 2013
  • Spotlight on Women in Medicine, Washington University School of Medicine, Invited Speaker2009
  • American Thoracic Society & chILD Travel Award2010
  • Pediatric UPDATE “Hyaline Membrane Disease and Other Surfactant Disorders.” Volume 32, Issue 8, Invited Discussant2011
  • NHLBI Workshop on Genomics and Lung Diseases2011
  • Japanese Respiratory Society, International Session Award2015
  • American Thoracic Society Meeting, Lead Facilitator for Thematic Poster Session: Lung Development, Pulmonary Hypertension, and Rare Lung Diseases2015
  • Childhood Interstitial Lung Disease (chILD) Annual Meeting, Invited Speaker, Genetic Disorders of Surfactant Function2015
  • NHLBI Workshop on Pediatric Rare Lung Diseases, Invited Participant2015
  • Childhood Interstitial Lung Disease (chILD) Surfactant Week, Invited Webinar Speaker2015
  • American Thoracic Society, Pediatric Core Curriculum, Invited Speaker2016
  • American Thoracic Society, Moderator for Poster Symposium, Neonatal and Congenital Lung Disorders2016
  • NIH Respiratory Integrative Biology and Translational Research Study Section, Early Career Reviewer2016
  • Illumina Whole Genome Sequencing Customer Advisory Group2017
  • Rare Pediatric Respiratory Disease: Science Shapes Precision Care, Scientific Advisory2017
  • Perinatal Institute, Cincinnati Children’s Hospital, Pulmonary Biology and Pulmonary Medicine, Invited Speaker2018
  • American Thoracic Society, Sunrise Seminar, What's all the VUS about testing for pediatric lung diseases?", Invited Speaker2018 - 2018

Selected Publications view all (38)

Remission of severe neonatal diabetes with very early sulfonylurea treatment. Diabetes Care. 2015;38(3):e38-9. doi:10.2337/dc14-2124  PMID:25715421 
Respiratory failure in a term infant with cis and trans mutations in ABCA3. J Perinatol. 2015;35(3):231-2. doi:10.1038/jp.2014.236  PMCID:PMC4341920   PMID:25712598 
New clinical practice guidelines on the classification, evaluation and management of childhood interstitial lung disease in infants: what do they mean? Expert Rev Respir Med. 2014;1-3. doi:10.1586/17476348.2014.951334  PMID:25138715 
Genotype-phenotype correlations for infants and children with ABCA3 deficiency. Am J Respir Crit Care Med. 2014;189(12):1538-43. doi:10.1164/rccm.201402-0342OC  PMID:24871971 
Synonymous ABCA3 variants do not increase risk for neonatal respiratory distress syndrome. J Pediatr. 2014;164(6):1316-1321.e3. doi:10.1016/j.jpeds.2014.02.021  PMCID:PMC4035386  PMID:24657120 
Two deletions overlapping a distant FOXF1 enhancer unravel the role of lncRNA LINC01081 in etiology of alveolar capillary dysplasia with misalignment of pulmonary veins. Am J Med Genet A. 2014. doi:10.1002/ajmg.a.36606  PMID:24842713 
Neural Tube Defect in Infant of Epileptic Mother Neoreviews. 2013;14:e412. 
Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum Mutat. 2013;34(6):801-11. doi:10.1002/humu.22313  PMCID:PMC3663886  PMID:23505205 
Visual Diagnosis: Term Newborn with Abdominal Wall Defect, Ambiguous Genitalia, and Respiratory Distress Neoreviews. 2013;14:e211. 
Single ABCA3 mutations increase risk for neonatal respiratory distress syndrome. Pediatrics. 2012;130(6):e1575-82. doi:10.1542/peds.2012-0918  PMCID:PMC3507255  PMID:23166334 
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