Jessica Pittman, M.D., M.P.H.  jpittman@wustl.edu

Assistant Professor of Pediatrics, Allergy, Immunology and Pulmonary Medicine
Patient Oriented Research UnitSchool of MedicineAllergy, Immunology and Pulmonary Medicine

phone: 314-454-2694

Research Interests


Dr. Pittman's primary research interest is improving the diagnosis and detection of early lung disease in infancy and early childhood through the use of novel outcome measures including infant pulmonary function testing and multiple breath washout (MBW) testing. She is a past recipient of the Cystic Fibrosis Foundation Leroy Matthews Physician/Scientist Award (2010 - 2013) and recently received an NIH K12 award through the Washington University School of Medicine Omics of Inflammatory Airways Disease K12 Program. She has served as the Associate Director of the Cystic Fibrosis Foundation Therapeutics Development Network Center for Infant and Preschool Pulmonary Function Testing since 2011; her lab focuses on improving the standardization of multiple breath washout testing and collecting normative data for MBW measures. Dr. Pittman has participated in research studies involving children with cystic fibrosis, primary ciliary dyskinesia, and asthma/wheeze, including several multi-center NIH studies. Her most recent research projects aim to improve our understanding of the pathophysiology of early childhood lung disease (particularly cystic fibrosis) by investigating the association of functional/physiologic measures (multiple breath washout testing, infant pulmonary function testing), imaging studies (ventilation studies using MRI), and more basic measures of disease such as the respiratory microbiome and pulmonary inflammatory markers.

Education

  • B.A., High Honors in Biology awarded June, 1998, Oberlin College1998
  • M.D., Washington University School of Medicine2004
  • MPH, University of North Carolina at Chapel Hill School of Public Health2009

Training

  • Pediatric Intern, University of Washington School of Medicine/ Seattle Children's Hospital & Regional Medical Center2004 - 2005
  • Pediatric Resident, University of Washington School of Medicine/ Seattle Children's Hospital & Regional Medical Center2005 - 2007
  • Associate Chief Pediatric Resident, University of Washington School of Medicine/ Seattle Children's Hospital & Regional Medical Center2007 - 2007
  • Fellow, Pediatric Pulmonology, University of North Carolina at Chapel Hill Hospitals2007 - 2011
  • Research Fellow, Division of Pediatric Respirology, Toronto Hospital for Sick Children2012 - 2012

Licensure and Board Certification

  • American Board of Pediatrics, General Pediatrics
  • American Board of Pediatrics, Pediatric Pulmonology
  • MO, Medical License, State of Missouri
  • NC, Medical License, State of North Carolina

Honors

  • Howard Hughes Summer Internship at the National Institutes of Health1995
  • Presidential Scholar, Oberlin College1995 - 1998
  • Project Excellence Minority Scholarship, Oberlin College1995 - 1998
  • Science Scholars Scholarship, Oberlin College1995 - 1998
  • National Institutes of Health Summer Intramural Research Training Award1996
  • Howard Hughes Summer Internship, Oberlin College1997
  • High Honors in Biology, Oberlin College1998
  • Sigma Xi, Oberlin College1998
  • Phi Beta Kappa, Oberlin College1998
  • Distinguished Alumni Scholarship, Washington University School of Medicine2000 - 2004
  • Olin Fellowship for Women, Washington University School of Medicine2000 - 2004
  • George F. Gill Prize in Pediatrics (for superior scholarship in pediatrics), Washington University School of Medicine2004
  • Abraham Bergman Prize, Harborview Medical Center, Seattle, WA, Department of Pediatrics. Given to the resident who most effectively acts to advance the well-being of children treated while providing exemplary care to pediatric patients and families.2006
  • Minority Trainee Travel Award, American Thoracic Society2008
  • Pulmonary/Critical Care Training Program Travel Scholarship, American Thoracic Society2009
  • Tunnessen Award for Clinical Science Research, Evening of Scholarship, University of North Carolina at Chapel Hill School of Medicine, Department of Pediatrics2009
  • Tunnessen Award for Clinical Science Research, Evening of Scholarship, University of North Carolina at Chapel Hill School of Medicine, Department of Pediatrics2010
  • 1st Prize, Clinical Fellows Abstract Award, University of North Carolina/Duke University Visiting Pulmonary Scholar Symposium2011
  • Assembly on Pediatrics Scientific Abstract Award, American Thoracic Society2011
  • Assembly on Pediatrics Travel Award, American Thoracic Society2011

Selected Publications view all (10)


Publication Co-Authors

  1. Leigh MW, Ferkol TW, Davis SD, Lee HS, Rosenfeld M, Dell SD, Sagel SD, Milla C, Olivier KN, Sullivan KM, Zariwala MA, Pittman J, Shapiro AJ, Carson JL, Krischer J, Hazucha MJ, Knowles MR. Clinical Features and Associated Likelihood of Primary Ciliary Dyskinesia in Children and Adolescents. Ann Am Thorac Soc. 2016. doi:10.1513/AnnalsATS.201511-748OC  PMID:27070726  
  2. Pittman, JE. Assessment and Detection of Early Lung Disease in Cystic Fibrosis Pediatr Allergy Immunol. 2015;28(4):212-219. 
  3. Pittman JE, Davis SD. Decline in Forced Expiratory Volume in 1 Second in Cystic Fibrosis--Watch the Pendulum Swing. J Pediatr. 2015. doi:10.1016/j.jpeds.2015.10.033  PMID:26547404  
  4. Subbarao P, Milla C, Aurora P, Davies JC, Davis SD, Hall GL, Heltshe S, Latzin P, Lindblad A, Pittman JE, Robinson PD, Rosenfeld M, Singer F, Starner TD, Ratjen F, Morgan W. Multiple-Breath Washout as a Lung Function Test in Cystic Fibrosis. A Cystic Fibrosis Foundation Workshop Report. Ann Am Thorac Soc. 2015;12(6):932-9. doi:10.1513/AnnalsATS.201501-021FR  PMID:26075554  
  5. Pittman JE, Ferkol TW. The Evolution of Cystic Fibrosis Care. Chest. 2015. doi:10.1378/chest.14-1997  PMID:25764168  
  6. Davis SD, Ferkol TW, Rosenfeld M, Lee HS, Dell SD, Sagel SD, Milla C, Zariwala MA, Pittman JE, Shapiro AJ, Carson JL, Krischer JP, Hazucha MJ, Cooper ML, Knowles MR, Leigh MW. Clinical features of childhood primary ciliary dyskinesia by genotype and ultrastructural phenotype. Am J Respir Crit Care Med. 2014. doi:10.1164/rccm.201409-1672OC  PMID:25493340  
  7. Pittman JE, Cutting G, Davis SD, Ferkol T, Boucher R. Cystic fibrosis: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Ann Am Thorac Soc. 2014;11(Suppl 3):S161-8. doi:10.1513/AnnalsATS.201312-444LD  PMID:24754825  
  8. Austin-Tse C, Halbritter J, Zariwala MA, Gilberti RM, Gee HY, Hellman N, Pathak N, Liu Y, Panizzi JR, Patel-King RS, Tritschler D, Bower R, O'Toole E, Porath JD, Hurd TW, Chaki M, Diaz KA, Kohl S, Lovric S, Hwang DY, Braun DA, Schueler M, Airik R, Otto EA, Leigh MW, Noone PG, Carson JL, Davis SD, Pittman JE, Ferkol TW, Atkinson JJ, Olivier KN, Sagel SD, Dell SD, Rosenfeld M, Milla CE, Loges NT, Omran H, Porter ME, King SM, Knowles MR, Drummond IA, Hildebrandt F. Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia. Am J Hum Genet. 2013;93(4):672-86. doi:10.1016/j.ajhg.2013.08.015  PMCID:PMC3791264  PMID:24094744  
  9. Zariwala MA, Gee HY, Kurkowiak M, Al-Mutairi DA, Leigh MW, Hurd TW, Hjeij R, Dell SD, Chaki M, Dougherty GW, Adan M, Spear PC, Esteve-Rudd J, Loges NT, Rosenfeld M, Diaz KA, Olbrich H, Wolf WE, Sheridan E, Batten TF, Halbritter J, Porath JD, Kohl S, Lovric S, Hwang DY, Pittman JE, Burns KA, Ferkol TW, Sagel SD, Olivier KN, Morgan LC, Werner C, Raidt J, Pennekamp P, Sun Z, Zhou W, Airik R, Natarajan S, Allen SJ, Amirav I, Wieczorek D, Landwehr K, Nielsen K, Schwerk N, Sertic J, Köhler G, Washburn J, Levy S, Fan S, Koerner-Rettberg C, Amselem S, Williams DS, Mitchell BJ, Drummond IA, Otto EA, Omran H, Knowles MR, Hildebrandt F. ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6. Am J Hum Genet. 2013;93(2):336-45. doi:10.1016/j.ajhg.2013.06.007  PMCID:PMC3738827  PMID:23891469  
  10. Pittman JE, Johnson RC, Jones PW, Davis SD. Variability of a closed, rebreathing setup for multiple breath wash-out testing in children. Pediatr Pulmonol. 2012;47(12):1242-50. doi:10.1002/ppul.22531  PMID:22467329