Pediatric Research

Francis Sessions Cole, III, M.D. cole@kids.wustl.edu

Division Chief, Newborn Medicine

Assistant Vice Chancellor for Children's Health

Chief Medical Officer, St. Louis Children's Hospital

Executive Vice Chair, Department of Pediatrics

Park J. White, M.D., Professor of Pediatrics

Professor of Cell Biology and Physiology

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Cell Biology & Physiology School of Medicine Newborn Medicine Pediatrics

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Education

BA, Amherst College, 1969
MD, Yale School of Medicine, 1973

Training

Clinical Fellow in Pediatrics, Harvard Medical School, 1973 - 1974
Internship, Boston Children’s Hospital/Harvard Medical School, 1973 - 1974
Residency, Boston Children’s Hospital/Harvard Medical School, 1976 - 1978
Clinical Fellow in Pediatrics, Harvard Medical School, 1976 - 1978
Research Fellow in Pediatrics, Harvard Medical School, 1978 - 1980
Research Fellow, Neonatology and Cell Biology, the Joint Program in Neonatology, Brigham and Women's Hospital, 1978 - 1981

Licensure and Board Certification

National Board of Medical Examiners, #134003 , 1973
MA, , 1975
American Board of Pediatrics #23915 , 1980
American Board of Neonatal-Perinatal Medicine (#1141) , 1983
MO, , 1986

Honors

Alpha Omega Alpha, Yale University School of Medicine, 1973
M.D., cum laude, Yale University School of Medicine, 1973
37th Annual Alpha Omega Alpha Lecturer, Washington University School of Medicine, 1990
Clinical Teacher of the Year Award, Washington University School of Medicine, 1993
Invited plenary session speaker, 14th European Congress of Perinatal Medicine, Helsinki, Finland, 1994
FDR Leadership Award from the March of Dimes (co-winner with Senator Christopher Bond, Senior Senator from Missouri), 1997
Distinguished Faculty Award-Founder's Day, Washington University, 1997
Named the Park J. White, M.D., Professor of Pediatrics, 1998
Distinguished Service Teaching Award, Washington University School of Medicine Class of 2001, 1998
Clinical Teaching Award, Washington University School of Medicine Class of 2000, 1999
Torch of Youth Award, National Council on Youth Leadership, 1999
Cartíer First Aide Award, St. Louis Effort For AIDS, 2000
Washington University Nominee for the Pfizer Humanism in Medicine Award, 2003
Distinguished Service Teaching Award, Washington University School of Medicine, Class of 2007, 2004
Washington University School of Medicine Distinguished Faculty Award Recipient for Distinguished Community Service, 2009
Princeton Award from the Princeton Club of St. Louis in recognition of outstanding leadership in service to the community, 2010
Washington University School of Medicine Samuel R. Goldstein Leadership Award in Medical Education, 2010
Distinguished Service Award from the Washington University Medical Center Alumni Association, 2013
Washington University School of Medicine 2nd Century Award, 2014
Distinguished Alumnus Award, Moses Brown School, Providence, Rhode Island, 2015
Founder's Award - Midwest Society for Pediatric Research (MWSPR), 2016
25th Anniversary Honorees, Heroes for Babies Award - March of Dimes, 2017

Selected Publications view all (112)

Publication Co-Authors

Marcia C. Willing, M.D., Ph. D.

Dustin Baldridge

Todd Druley, M.D., Ph.D.

Shawn O'Connor

Stuart C. Sweet, M.D., Ph.D.

Marwan Shinawi, M.D.

Jagruti Anadkat, M.D.

Philip Levy, M.D.

Andrew J. White, M.D.

Jennifer A Wambach, M.D.

Zachary A. Vesoulis, M.D.

Christine M. Hrach, M.D.

Dorothy Katherine Grange, M.D.

Michael P. Turmelle, M.D.

Danielle Alfano

Jennifer N. Avari Silva, M.D.

R. Mark Grady, M.D.

Kevin T. Barton, M.D.

Kathryn Leonard

Schwartz, Alan L., Ph.D., M.D.

1.	Ng BG, Shiryaev SA, Rymen D, Eklund EA, Raymond K, Kircher M, Abdenur JE, Alehan F, Midro AT, Bamshad MJ, Barone R, Berry GT, Brumbaugh JE, Buckingham KJ, Clarkson K, Cole FS, O'Connor S, Cooper GM, Van Coster R, Demmer LA, Diogo L, Fay AJ, Ficicioglu C, Fiumara A, Gahl WA, Ganetzky R, Goel H, Harshman LA, He M, Jaeken J, James PM, Katz D, Keldermans L, Kibaek M, Kornberg AJ, Lachlan K, Lam C, Yaplito-Lee J, Nickerson DA, Peters HL, Race V, Régal L, Rush JS, Rutledge SL, Shendure J, Souche E, Sparks SE, Trapane P, Sanchez-Valle A, Vilain E, Vøllo A, Waechter CJ, Wang RY, Wolfe LA, Wong DA, Wood T, Yang AC, University of Washington Center for Mendelian Genomics, Matthijs G, Freeze HH. ALG1-CDG: Clinical and Molecular Characterization of 39 Unreported Patients. Hum Mutat. 2016;37(7):653-60. PMCID:PMC4907823 PMID:26931382
2.	Shen CL, Zhang Q, Meyer Hudson J, Cole FS, Wambach JA. Genetic Factors Contribute to Risk for Neonatal Respiratory Distress Syndrome among Moderately Preterm, Late Preterm, and Term Infants. J Pediatr. 2016;172:69-74.e2. PMCID:PMC4876036 PMID:26935785
3.	Jackson T, Wegner DJ, White FV, Hamvas A, Cole FS, Wambach JA. Respiratory failure in a term infant with cis and trans mutations in ABCA3. J Perinatol. 2015;35(3):231-2. doi:10.1038/jp.2014.236 PMCID:PMC4341920 PMID:25712598
4.	Vesoulis ZA, Attarian SJ, Zeller B, Cole FS. Minoxidil-associated anorexia in an infant with refractory hypertension. Pharmacotherapy. 2014;34(12):e341-4. doi:10.1002/phar.1495 PMID:25280267
5.	Starmer AJ, Spector ND, Srivastava R, West DC, Rosenbluth G, Allen AD, Noble EL, Tse LL, Dalal AK, Keohane CA, Lipsitz SR, Rothschild JM, Wien MF, Yoon CS, Zigmont KR, Wilson KM, O'Toole JK, Solan LG, Aylor M, Bismilla Z, Coffey M, Mahant S, Blankenburg RL, Destino LA, Everhart JL, Patel SJ, Bale JF Jr, Spackman JB, Stevenson AT, Calaman S, Cole FS, Balmer DF, Hepps JH, Lopreiato JO, Yu CE, Sectish TC, Landrigan CP, I-PASS Study Group. Changes in medical errors after implementation of a handoff program. N Engl J Med. 2014;371(19):1803-12. doi:10.1056/NEJMsa1405556 PMID:25372088
6.	Szafranski P, Dharmadhikari AV, Wambach JA, Towe CT, White FV, Grady RM, Eghtesady P, Cole FS, Deutsch G, Sen P, Stankiewicz P. Two deletions overlapping a distant FOXF1 enhancer unravel the role of lncRNA LINC01081 in etiology of alveolar capillary dysplasia with misalignment of pulmonary veins. Am J Med Genet A. 2014;164A(8):2013-9. doi:10.1002/ajmg.a.36606 PMCID:PMC4107046 PMID:24842713
7.	Wambach JA, Casey AM, Fishman MP, Wegner DJ, Wert SE, Cole FS, Hamvas A, Nogee LM. Genotype-phenotype correlations for infants and children with ABCA3 deficiency. Am J Respir Crit Care Med. 2014;189(12):1538-43. doi:10.1164/rccm.201402-0342OC PMCID:PMC4226019 PMID:24871971
8.	Starmer AJ, O'Toole JK, Rosenbluth G, Calaman S, Balmer D, West DC, Bale JF Jr, Yu CE, Noble EL, Tse LL, Srivastava R, Landrigan CP, Sectish TC, Spector ND, I-PASS Study Education Executive Committee. Development, implementation, and dissemination of the I-PASS handoff curriculum: A multisite educational intervention to improve patient handoffs. Acad Med. 2014;89(6):876-84. doi:10.1097/ACM.0000000000000264 PMID:24871238

1.	Stout MJ, Demaree D, Merfeld E, Tuuli MG, Wambach JA, Cole FS, Cahill AG. Neonatal Outcomes Differ after Spontaneous and Indicated Preterm Birth. Am J Perinatol. 2018;35(5):494-502. PMID:29183099
2.	Towe CT, White FV, Grady RM, Sweet SC, Eghtesady P, Wegner DJ, Sen P, Szafranski P, Stankiewicz P, Hamvas A, Cole FS, Wambach JA. Infants with Atypical Presentations of Alveolar Capillary Dysplasia with Misalignment of the Pulmonary Veins Who Underwent Bilateral Lung Transplantation. J Pediatr. 2017. PMID:29198536
3.	Wambach JA, Stettner GM, Haack TB, Writzl K, Škofljanec A, Maver A, Munell F, Ossowski S, Bosio M, Wegner DJ, Shinawi M, Baldridge D, Alhaddad B, Strom TM, Grange DK, Wilichowski E, Troxell R, Collins J, Warner BB, Schmidt RE, Pestronk A, Cole FS, Steinfeld R. Survival among children with "Lethal" congenital contracture syndrome 11 caused by novel mutations in the gliomedin gene (GLDN). Hum Mutat. 2017;38(11):1477-1484. PMCID:PMC5638693 PMID:28726266
4.	Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, Traber K, Quinton LJ, Crane A, Davis BR, White FV, Wambach J, Whitsett JA, Cole FS, Morrisey EE, Guttentag SH, Beers MF, Kotton DN. Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells. Cell Stem Cell. 2017;21(4):472-488.e10. PMCID:PMC5755620 PMID:28965766
5.	Cole FS, Wegner DJ, Davis JM. The Genomics of Neonatal Abstinence Syndrome. Front Pediatr. 2017;5:176. PMCID:PMC5572235 PMID:28879171
6.	Starmer AJ, Spector ND, West DC, Srivastava R, Sectish TC, Landrigan CP, I-PASS Study Group.. Integrating Research, Quality Improvement, and Medical Education for Better Handoffs and Safer Care: Disseminating, Adapting, and Implementing the I-PASS Program. Jt Comm J Qual Patient Saf. 2017;43(7):319-329. PMID:28648217
7.	Coffey M, Thomson K, Li SA, Bismilla Z, Starmer AJ, O'Toole JK, Blankenburg RL, Rosenbluth G, Cole FS, Yu CE, Hepps JH, Sectish TC, Spector ND, Srivastava R, Allen AD, Mahant S, Landrigan CP. Resident Experiences With Implementation of the I-PASS Handoff Bundle. J Grad Med Educ. 2017;9(3):313-320. PMCID:PMC5476380 PMID:28638509
8.	Eldridge WB, Zhang Q, Faro A, Sweet SC, Eghtesady P, Hamvas A, Cole FS, Wambach JA. Outcomes of Lung Transplantation for Infants and Children with Genetic Disorders of Surfactant Metabolism. J Pediatr. 2017;184:157-164.e2. PMCID:PMC5443678 PMID:28215425
9.	Khan A, Coffey M, Litterer KP, Baird JD, Furtak SL, Garcia BM, Ashland MA, Calaman S, Kuzma NC, O'Toole JK, Patel A, Rosenbluth G, Destino LA, Everhart JL, Good BP, Hepps JH, Dalal AK, Lipsitz SR, Yoon CS, Zigmont KR, Srivastava R, Starmer AJ, Sectish TC, Spector ND, West DC, Landrigan CP, and the Patient and Family Centered I-PASS Study Group., Allair BK, Alminde C, Alvarado-Little W, Atsatt M, Aylor ME, Bale JF Jr, Balmer D, Barton KT, Beck C, Bismilla Z, Blankenberg RL, Chandler D, Choudhary A, Christensen E, Coghlan-McDonald S, Cole FS, Corless E, Cray S, Da Silva R, Dahale D, Dreyer B, Growdon AS, Gubler L, Guiot A, Harris R, Haskell H, Kocolas I, Kruvand E, Lane MM, Langrish K, Ledford CJ, Lewis K, Lopreiato JO, Maloney CG, Mangan A, Markle P, Mendoza F, Micalizzi DA, Mittal V, Obermeyer M, O'Donnell KA, Ottolini M, Patel SJ, Pickler R, Rogers JE, Sanders LM, Sauder K, Shah SS, Sharma M, Simpkin A, Subramony A, Thompson ED Jr, Trueman L, Trujillo T, Turmelle MP, Warnick C, Welch C, White AJ, Wien MF, Winn AS, Wintch S, Wolf M, Yin HS, Yu CE. Families as Partners in Hospital Error and Adverse Event Surveillance. JAMA Pediatr. 2017;171(4):372-381. PMID:28241211
10.	Wambach JA, Yang P, Wegner DJ, Heins HB, Kaliberova LN, Kaliberov SA, Curiel DT, White FV, Hamvas A, Hackett BP, Cole FS. Functional Characterization of ATP-Binding Cassette Transporter A3 Mutations from Infants with Respiratory Distress Syndrome. Am J Respir Cell Mol Biol. 2016;55(5):716-721. PMCID:PMC5105181 PMID:27374344
11.	Ng BG, Shiryaev SA, Rymen D, Eklund EA, Raymond K, Kircher M, Abdenur JE, Alehan F, Midro AT, Bamshad MJ, Barone R, Berry GT, Brumbaugh JE, Buckingham KJ, Clarkson K, Cole FS, O'Connor S, Cooper GM, Van Coster R, Demmer LA, Diogo L, Fay AJ, Ficicioglu C, Fiumara A, Gahl WA, Ganetzky R, Goel H, Harshman LA, He M, Jaeken J, James PM, Katz D, Keldermans L, Kibaek M, Kornberg AJ, Lachlan K, Lam C, Yaplito-Lee J, Nickerson DA, Peters HL, Race V, Régal L, Rush JS, Rutledge SL, Shendure J, Souche E, Sparks SE, Trapane P, Sanchez-Valle A, Vilain E, Vøllo A, Waechter CJ, Wang RY, Wolfe LA, Wong DA, Wood T, Yang AC, University of Washington Center for Mendelian Genomics, Matthijs G, Freeze HH. ALG1-CDG: Clinical and Molecular Characterization of 39 Unreported Patients. Hum Mutat. 2016;37(7):653-60. PMCID:PMC4907823 PMID:26931382
12.	Shen CL, Zhang Q, Meyer Hudson J, Cole FS, Wambach JA. Genetic Factors Contribute to Risk for Neonatal Respiratory Distress Syndrome among Moderately Preterm, Late Preterm, and Term Infants. J Pediatr. 2016;172:69-74.e2. PMCID:PMC4876036 PMID:26935785
13.	Chen YJ, Wambach JA, DePass K, Wegner DJ, Chen SK, Zhang QY, Heins H, Cole FS, Hamvas A. Population-based frequency of surfactant dysfunction mutations in a native Chinese cohort. World J Pediatr. 2016;12(2):190-5. PMID:26547207
14.	Jackson T, Wegner DJ, White FV, Hamvas A, Cole FS, Wambach JA. Respiratory failure in a term infant with cis and trans mutations in ABCA3. J Perinatol. 2015;35(3):231-2. doi:10.1038/jp.2014.236 PMCID:PMC4341920 PMID:25712598
15.	Vesoulis ZA, Attarian SJ, Zeller B, Cole FS. Minoxidil-associated anorexia in an infant with refractory hypertension. Pharmacotherapy. 2014;34(12):e341-4. doi:10.1002/phar.1495 PMID:25280267
16.	Starmer AJ, Spector ND, Srivastava R, West DC, Rosenbluth G, Allen AD, Noble EL, Tse LL, Dalal AK, Keohane CA, Lipsitz SR, Rothschild JM, Wien MF, Yoon CS, Zigmont KR, Wilson KM, O'Toole JK, Solan LG, Aylor M, Bismilla Z, Coffey M, Mahant S, Blankenburg RL, Destino LA, Everhart JL, Patel SJ, Bale JF Jr, Spackman JB, Stevenson AT, Calaman S, Cole FS, Balmer DF, Hepps JH, Lopreiato JO, Yu CE, Sectish TC, Landrigan CP, I-PASS Study Group. Changes in medical errors after implementation of a handoff program. N Engl J Med. 2014;371(19):1803-12. doi:10.1056/NEJMsa1405556 PMID:25372088
17.	Szafranski P, Dharmadhikari AV, Wambach JA, Towe CT, White FV, Grady RM, Eghtesady P, Cole FS, Deutsch G, Sen P, Stankiewicz P. Two deletions overlapping a distant FOXF1 enhancer unravel the role of lncRNA LINC01081 in etiology of alveolar capillary dysplasia with misalignment of pulmonary veins. Am J Med Genet A. 2014;164A(8):2013-9. doi:10.1002/ajmg.a.36606 PMCID:PMC4107046 PMID:24842713
18.	Wambach JA, Casey AM, Fishman MP, Wegner DJ, Wert SE, Cole FS, Hamvas A, Nogee LM. Genotype-phenotype correlations for infants and children with ABCA3 deficiency. Am J Respir Crit Care Med. 2014;189(12):1538-43. doi:10.1164/rccm.201402-0342OC PMCID:PMC4226019 PMID:24871971
19.	Starmer AJ, O'Toole JK, Rosenbluth G, Calaman S, Balmer D, West DC, Bale JF Jr, Yu CE, Noble EL, Tse LL, Srivastava R, Landrigan CP, Sectish TC, Spector ND, I-PASS Study Education Executive Committee. Development, implementation, and dissemination of the I-PASS handoff curriculum: A multisite educational intervention to improve patient handoffs. Acad Med. 2014;89(6):876-84. doi:10.1097/ACM.0000000000000264 PMID:24871238
20.	Wambach JA, Wegner DJ, Heins HB, Druley TE, Mitra RD, Hamvas A, Cole FS. Synonymous ABCA3 variants do not increase risk for neonatal respiratory distress syndrome. J Pediatr. 2014;164(6):1316-1321.e3. doi:10.1016/j.jpeds.2014.02.021 PMCID:PMC4035386 PMID:24657120
21.	Ramos EI, Bien-Willner GA, Li J, Hughes AE, Giacalone J, Chasnoff S, Kulkarni S, Parmacek M, Cole FS, Druley TE. Genetic variation in MKL2 and decreased downstream PCTAIRE1 expression in extreme, fatal primary human microcephaly. Clin Genet. 2014;85(5):423-32. doi:10.1111/cge.12197 PMCID:PMC3929543 PMID:23692340
22.	O'Toole JK, West DC, Starmer AJ, Yu CE, Calaman S, Rosenbluth G, Hepps JH, Lopreiato JO, Landrigan CP, Sectish TC, Spector ND, I-PASS Study Education Executive Committee. Placing faculty development front and center in a multisite educational initiative: lessons from the I-PASS Handoff study. Acad Pediatr. 2014;14(3):221-4. doi:10.1016/j.acap.2014.02.013 PMID:24767774
23.	Coghlan MA, Shifren A, Huang HJ, Russell TD, Mitra RD, Zhang Q, Wegner DJ, Cole FS, Hamvas A. Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations. BMJ Open Respir Res. 2014;1(1):e000057. doi:10.1136/bmjresp-2014-000057 PMCID:PMC4265083 PMID:25553246
24.	van Meel E, Wegner DJ, Cliften P, Willing MC, White FV, Kornfeld S, Cole FS. Rare recessive loss-of-function methionyl-tRNA synthetase mutations presenting as a multi-organ phenotype. BMC Med Genet. 2013;14(1):106. doi:10.1186/1471-2350-14-106 PMID:24103465
25.	Hamvas A, Deterding RR, Wert SE, White FV, Dishop MK, Alfano DN, Halbower AC, Planer B, Stephan MJ, Uchida DA, Williames LD, Rosenfeld JA, Lebel RR, Young LR, Cole FS, Nogee LM. Heterogeneous pulmonary phenotypes associated with mutations in the thyroid transcription factor gene NKX2-1. Chest. 2013;144(3):794-804. doi:10.1378/chest.12-2502 PMCID:PMC3760742 PMID:23430038
26.	Wilfond BS, Magnus D, Antommaria AH, Appelbaum P, Aschner J, Barrington KJ, Beauchamp T, Boss RD, Burke W, Caplan AL, Capron AM, Cho M, Clayton EW, Cole FS, Darlow BA, Diekema D, Faden RR, Feudtner C, Fins JJ, Fost NC, Frader J, Hester DM, Janvier A, Joffe S, Kahn J, Kass NE, Kodish E, Lantos JD, McCullough L, McKinney R Jr, Meadow W, O'Rourke PP, Powderly KE, Pursley DM, Ross LF, Sayeed S, Sharp RR, Sugarman J, Tarnow-Mordi WO, Taylor H, Tomlinson T, Truog RD, Unguru YT, Weise KL, Woodrum D, Youngner S. The OHRP and SUPPORT. N Engl J Med. 2013;368(25):e36. doi:10.1056/NEJMc1307008 PMID:23738513
27.	Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P. Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum Mutat. 2013;34(6):801-11. doi:10.1002/humu.22313 PMCID:PMC3663886 PMID:23505205
28.	Anderson JL, Levy PT, Leonard KB, Smyser CD, Tychsen L, Cole FS. Congenital lymphocytic choriomeningitis virus: when to consider the diagnosis. J Child Neurol. 2013;29(6):837-842. doi:10.1177/0883073813486295 PMCID:PMC3972356 PMID:23666045
29.	Mills KI, Anderson J, Levy PT, Cole FS, Silva JN, Kulkarni S, Shinawi M. Duplication of 20p12.3 associated with familial Wolff-Parkinson-White syndrome. Am J Med Genet A. 2013;161A(1):137-44. doi:10.1002/ajmg.a.35701 PMID:23239491
30.	Wambach JA, Wegner DJ, Depass K, Heins H, Druley TE, Mitra RD, An P, Zhang Q, Nogee LM, Cole FS, Hamvas A. Single ABCA3 mutations increase risk for neonatal respiratory distress syndrome. Pediatrics. 2012;130(6):e1575-82. doi:10.1542/peds.2012-0918 PMCID:PMC3507255 PMID:23166334
31.	Anadkat JS, Kuzniewicz MW, Chaudhari BP, Cole FS, Hamvas A. Increased risk for respiratory distress among white, male, late preterm and term infants. J Perinatol. 2012;32(10):780-5. doi:10.1038/jp.2011.191 PMCID:PMC3461404 PMID:22222548
32.	Bereman MS, Tomazela DM, Heins HS, Simonato M, Cogo PE, Hamvas A, Patterson BW, Cole FS, MacCoss MJ. A method to determine the kinetics of multiple proteins in human infants with respiratory distress syndrome. Anal Bioanal Chem. 2012;403(8):2397-402. doi:10.1007/s00216-012-5953-3 PMID:22526637
33.	Agrawal A, Hamvas A, Cole FS, Wambach JA, Wegner D, Coghill C, Harrison K, Nogee LM. An intronic ABCA3 mutation that is responsible for respiratory disease. Pediatr Res. 2012;71(6):633-7. doi:10.1038/pr.2012.21 PMID:22337229
34.	Starmer AJ, Spector ND, Srivastava R, Allen AD, Landrigan CP, Sectish TC, I-PASS Study Group. I-pass, a mnemonic to standardize verbal handoffs. Pediatrics. 2012;129(2):201-4. doi:10.1542/peds.2011-2966 PMID:22232313
35.	Sectish TC, Starmer AJ, Landrigan CP, Spector ND, I-PASS Study Group. Establishing a multisite education and research project requires leadership, expertise, collaboration, and an important aim. Pediatrics. 2010;126(4):619-22. doi:10.1542/peds.2010-1793 PMID:20876168
36.	Wambach JA, Yang P, Wegner DJ, An P, Hackett BP, Cole FS, Hamvas A. Surfactant protein-C promoter variants associated with neonatal respiratory distress syndrome reduce transcription. Pediatr Res. 2010;68(3):216-20. doi:10.1203/PDR.0b013e3181eb5d68 PMCID:PMC2921462 PMID:20539253
37.	Tomazela DM, Patterson BW, Hanson E, Spence KL, Kanion TB, Salinger DH, Vicini P, Barret H, Heins HB, Cole FS, Hamvas A, MacCoss MJ. Measurement of human surfactant protein-B turnover in vivo from tracheal aspirates using targeted proteomics. Anal Chem. 2010;82(6):2561-7. doi:10.1021/ac1001433 PMCID:PMC2843406 PMID:20178338
38.	Hamvas A, Nogee LM, Wegner DJ, Depass K, Christodoulou J, Bennetts B, McQuade LR, Gray PH, Deterding RR, Carroll TR, Kammesheidt A, Kasch LM, Kulkarni S, Cole FS. Inherited surfactant deficiency caused by uniparental disomy of rare mutations in the surfactant protein-B and ATP binding cassette, subfamily a, member 3 genes. J Pediatr. 2009;155(6):854-859.e1. doi:10.1016/j.jpeds.2009.06.006 PMCID:PMC2794197 PMID:19647838
39.	Druley TE, Vallania FL, Wegner DJ, Varley KE, Knowles OL, Bonds JA, Robison SW, Doniger SW, Hamvas A, Cole FS, Fay JC, Mitra RD. Quantification of rare allelic variants from pooled genomic DNA. Nat Methods. 2009;6(4):263-5. doi:10.1038/nmeth.1307 PMCID:PMC2776647 PMID:19252504
40.	Hamvas A, Heins HB, Guttentag SH, Wegner DJ, Trusgnich MA, Bennet KW, Yang P, Carlson CS, An P, Cole FS. Developmental and genetic regulation of human surfactant protein B in vivo. Neonatology. 2009;95(2):117-24. doi:10.1159/000153095 PMCID:PMC2765709 PMID:18776725
41.	Garmany TH, Wambach JA, Heins HB, Watkins-Torry JM, Wegner DJ, Bennet K, An P, Land G, Saugstad OD, Henderson H, Nogee LM, Cole FS, Hamvas A. Population and disease-based prevalence of the common mutations associated with surfactant deficiency. Pediatr Res. 2008;63(6):645-9. doi:10.1203/PDR.0b013e31816fdbeb PMCID:PMC2765719 PMID:18317237
42.	McBee AD, Wegner DJ, Carlson CS, Wambach JA, Yang P, Heins HB, Saugstad OD, Trusgnich MA, Watkins-Torry J, Nogee LM, Henderson H, Cole FS, Hamvas A. Recombination as a mechanism for sporadic mutation in the surfactant protein-C gene. Pediatr Pulmonol. 2008;43(5):443-50. doi:10.1002/ppul.20782 PMCID:PMC2765708 PMID:18383112
43.	Hamvas A, Wegner DJ, Carlson CS, Bergmann KR, Trusgnich MA, Fulton L, Kasai Y, An P, Mardis ER, Wilson RK, Cole FS. Comprehensive genetic variant discovery in the surfactant protein B gene. Pediatr Res. 2007;62(2):170-5. doi:10.1203/PDR.0b013e3180a03232 PMCID:PMC2765713 PMID:17597650
44.	Wegner DJ, Hertzberg T, Heins HB, Elmberger G, MacCoss MJ, Carlson CS, Nogee LM, Cole FS, Hamvas A. A major deletion in the surfactant protein-B gene causing lethal respiratory distress. Acta Paediatr. 2007;96(4):516-20. doi:10.1111/j.1651-2227.2006.00188.x PMID:17391469
45.	Saugstad OD, Hansen TW, Rønnestad A, Nakstad B, Tølløfsrud PA, Reinholt F, Hamvas A, Coles FS, Dean M, Wert SE, Whitsett JA, Nogee LM. Novel mutations in the gene encoding ATP binding cassette protein member A3 (ABCA3) resulting in fatal neonatal lung disease. Acta Paediatr. 2007;96(2):185-90. PMID:17429902
46.	Kistka ZA, Palomar L, Lee KA, Boslaugh SE, Wangler MF, Cole FS, DeBaun MR, Muglia LJ. Racial disparity in the frequency of recurrence of preterm birth. Am J Obstet Gynecol. 2007;196(2):131.e1-6. doi:10.1016/j.ajog.2006.06.093 PMID:17306652
47.	Hamvas A, Cole FS, Nogee LM. Genetic disorders of surfactant proteins. Neonatology. 2007;91(4):311-7. doi:10.1159/000101347 PMID:17575475
48.	Cole FS, Nogee LM, Hamvas A. Defects in surfactant synthesis: clinical implications. Pediatr Clin North Am. 2006;53(5):911-27, ix. doi:10.1016/j.pcl.2006.08.006 PMID:17027617
49.	Palomar LM, Nogee LM, Sweet SC, Huddleston CB, Cole FS, Hamvas A. Long-term outcomes after infant lung transplantation for surfactant protein B deficiency related to other causes of respiratory failure. J Pediatr. 2006;149(4):548-53. doi:10.1016/j.jpeds.2006.06.004 PMID:17011330
50.	Hamvas A, Wegner DJ, Trusgnich MA, Madden K, Heins H, Liu Y, Rice T, An P, Watkins-Torry J, Cole FS. Genetic variant characterization in intron 4 of the surfactant protein B gene. Hum Mutat. 2005;26(5):494-5. doi:10.1002/humu.9378 PMID:16211553
51.	Hamvas A, Madden KK, Nogee LM, Trusgnich MA, Wegner DJ, Heins HB, Cole FS. Informed consent for genetic research. Arch Pediatr Adolesc Med. 2004;158(6):551-5. doi:10.1001/archpedi.158.6.551 PMID:15184218
52.	Cole FS. Surfactant protein B: unambiguously necessary for adult pulmonary function. Am J Physiol Lung Cell Mol Physiol. 2003;285(3):L540-2. doi:10.1152/ajplung.00111.2003 PMID:12902317
53.	Wilson RK, Ley TJ, Cole FS, Milbrandt JD, Clifton S, Fulton L, Fewell G, Minx P, Sun H, McLellan M, Pohl C, Mardis ER. Mutational profiling in the human genome. Cold Spring Harb Symp Quant Biol. 2003;68:23-9. PMID:15338599
54.	Hamvas A, Trusgnich M, Brice H, Baumgartner J, Hong Y, Nogee LM, Cole FS. Population-based screening for rare mutations: high-throughput DNA extraction and molecular amplification from Guthrie cards. Pediatr Res. 2001;50(5):666-8. doi:10.1203/00006450-200111000-00021 PMID:11641464
55.	Cole FS, Hamvas A, Nogee LM. Genetic disorders of neonatal respiratory function. Pediatr Res. 2001;50(2):157-62. doi:10.1203/00006450-200108000-00001 PMID:11477198
56.	Merchak A, Lueder GT, White FV, Cole FS. Alveolar capillary dysplasia with misalignment of pulmonary veins and anterior segment dysgenesis of the eye: a report of a new association and review of the literature. J Perinatol. 2001;21(5):327-30. doi:10.1038/sj.jp.7200494 PMID:11536028
57.	Cole FS, Hamvas A, Rubinstein P, King E, Trusgnich M, Nogee LM, deMello DE, Colten HR. Population-based estimates of surfactant protein B deficiency. Pediatrics. 2000;105(3 Pt 1):538-41. PMID:10699106
58.	Hamvas A, Kwong P, DeBaun M, Schramm W, Cole FS. Hyaline membrane disease is underreported in a linked birth-infant death certificate database. Am J Public Health. 1998;88(9):1387-9. PMCID:PMC1509088 PMID:9736884
59.	Chen B, Basil JB, Schefft GL, Cole FS, Sadovsky Y. Antenatal steroids and intraventricular hemorrhage after premature rupture of membranes at 24-28 weeks' gestation. Am J Perinatol. 1997;14(3):171-6. doi:10.1055/s-2007-994121 PMID:9259922
60.	Kempe A, Wise PH, Wampler NS, Cole FS, Wallace H, Dickinson C, Rinehart H, Lezotte DC, Beaty B. Risk status at discharge and cause of death for postneonatal infant deaths: a total population study. Pediatrics. 1997;99(3):338-44. PMID:9041284
61.	Hamvas A, Nogee LM, Mallory GB Jr, Spray TL, Huddleston CB, August A, Dehner LP, deMello DE, Moxley M, Nelson R, Cole FS, Colten HR. Lung transplantation for treatment of infants with surfactant protein B deficiency. J Pediatr. 1997;130(2):231-9. PMID:9042125
62.	Hamvas A, Wise PH, Yang RK, Wampler NS, Noguchi A, Maurer MM, Walentik CA, Schramm WF, Cole FS. The influence of the wider use of surfactant therapy on neonatal mortality among blacks and whites. N Engl J Med. 1996;334(25):1635-40. doi:10.1056/NEJM199606203342504 PMID:8628359
63.	Kilani RA, Cole FS, Bier DM. Phenylalanine hydroxylase activity in preterm infants: is tyrosine a conditionally essential amino acid? Am J Clin Nutr. 1995;61(6):1218-23. PMID:7762520
64.	Sunwood J, Brenman A, Escobedo J, Philpott T, Allman K, Mueller J, Jaeger J, Brown LK, Cole FS. School-based AIDS education for adolescents. J Adolesc Health. 1995;16(4):309-15. PMID:7612637
65.	Hamvas A, Nogee LM, deMello DE, Cole FS. Pathophysiology and treatment of surfactant protein-B deficiency. Biol Neonate. 1995;67 Suppl 1:18-31. PMID:7647155
66.	Khurana A, Huettner PC, Cole FS. Umbilical cord ulceration as a cause of hypoxic-ischemic encephalopathy: report of a case and review of the literature. J Perinatol. 1995;15(5):423-5. PMID:8576764
67.	DeBaun M, Rowley D, Province M, Stockbauer JW, Cole FS. Selected antepartum medical complications and very-low-birthweight infants among black and white women. Am J Public Health. 1994;84(9):1495-7. PMCID:PMC1615154 PMID:8092380
68.	Hamvas A, Cole FS, deMello DE, Moxley M, Whitsett JA, Colten HR, Nogee LM. Surfactant protein B deficiency: antenatal diagnosis and prospective treatment with surfactant replacement. J Pediatr. 1994;125(3):356-61. PMID:8071741
69.	deMello DE, Heyman S, Phelps DS, Hamvas A, Nogee L, Cole S, Colten HR. Ultrastructure of lung in surfactant protein B deficiency. Am J Respir Cell Mol Biol. 1994;11(2):230-9. doi:10.1165/ajrcmb.11.2.8049084 PMID:8049084
70.	Strunk RC, Fleischer JA, Katz Y, Cole FS. Developmentally regulated effects of lipopolysaccharide on biosynthesis of the third component of complement and factor B in human fibroblasts and monocytes. Immunology. 1994;82(2):314-20. PMCID:PMC1414817 PMID:7927503
71.	Hamvas A, Devine T, Cole FS. Surfactant therapy failure identifies infants at risk for pulmonary mortality. Am J Dis Child. 1993;147(6):665-8. PMID:8506837
72.	Coffin CM, Schechtman K, Cole FS, Dehner LP. Neonatal and infantile pulmonary hemorrhage: an autopsy study with clinical correlation. Pediatr Pathol. 1993;13(5):583-9. PMID:8247956
73.	Fjeld CR, Cole FS, Bier DM. Energy expenditure, lipolysis, and glucose production in preterm infants treated with theophylline. Pediatr Res. 1992;32(6):693-8. doi:10.1203/00006450-199212000-00015 PMID:1287561
74.	Kempe A, Wise PH, Barkan SE, Sappenfield WM, Sachs B, Gortmaker SL, Sobol AM, First LR, Pursley D, Rinehart H. Clinical determinants of the racial disparity in very low birth weight. N Engl J Med. 1992;327(14):969-73. doi:10.1056/NEJM199210013271401 PMID:1518548
75.	Johnson CA, Densen P, Wetsel RA, Cole FS, Goeken NE, Colten HR. Molecular heterogeneity of C2 deficiency. N Engl J Med. 1992;326(13):871-4. doi:10.1056/NEJM199203263261306 PMID:1542325
76.	Porter FL, Miller JP, Cole FS, Marshall RE. A controlled clinical trial of local anesthesia for lumbar punctures in newborns. Pediatrics. 1991;88(4):663-9. PMID:1896268
77.	Lennartz MR, Cole FS, Stahl PD. Biosynthesis and processing of the mannose receptor in human macrophages. J Biol Chem. 1989;264(4):2385-90. PMID:2914913
78.	Whyte MP, Mahuren JD, Fedde KN, Cole FS, McCabe ER, Coburn SP. Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5'-phosphate. Evidence for an ectoenzyme role for tissue-nonspecific alkaline phosphatase. J Clin Invest. 1988;81(4):1234-9. doi:10.1172/JCI113440 PMCID:PMC329654 PMID:3350970
79.	Katz Y, Cole FS, Strunk RC. Synergism between gamma interferon and lipopolysaccharide for synthesis of factor B, but not C2, in human fibroblasts. J Exp Med. 1988;167(1):1-14. PMCID:PMC2188816 PMID:3121777
80.	Lennartz MR, Cole FS, Shepherd VL, Wileman TE, Stahl PD. Isolation and characterization of a mannose-specific endocytosis receptor from human placenta. J Biol Chem. 1987;262(21):9942-4. PMID:3611070
81.	Perlmutter DH, Strunk RC, Goldberger G, Cole FS. Regulation of complement proteins C2 and factor B by interleukin-1 and interferon-gamma acting on transfected L cells. Mol Immunol. 1986;23(11):1263-6. PMID:3029573
82.	Royer-Pokora B, Kunkel LM, Monaco AP, Goff SC, Newburger PE, Baehner RL, Cole FS, Curnutte JT, Orkin SH. Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location. Nature. 1986;322:32-8. doi:10.1038/322032a0 PMID:2425263
83.	Sutton MB, Strunk RC, Cole FS. Regulation of the synthesis of the third component of complement and factor B in cord blood monocytes by lipopolysaccharide. J Immunol. 1986;136(4):1366-72. PMID:3003195
84.	Royer-Pokora B, Kunkel LM, Monaco AP, Goff SC, Newburger PE, Baehner RL, Cole FS, Curnutte JT, Orkin SH. Cloning the gene for the inherited disorder chronic granulomatous disease on the basis of its chromosomal location. Cold Spring Harb Symp Quant Biol. 1986;51 Pt 1:177-83. PMID:3472714
85.	Strunk RC, Cole FS, Perlmutter DH, Colten HR. gamma-Interferon increases expression of class III complement genes C2 and factor B in human monocytes and in murine fibroblasts transfected with human C2 and factor B genes. J Biol Chem. 1985;260(28):15280-5. PMID:2866182
86.	Zannis VI, Ordovas JM, Cladaras C, Cole FS, Forbes G, Schaefer EJ. mRNA and apolipoprotein E synthesis abnormalities in peripheral blood monocyte macrophages in familial apolipoprotein E deficiency. J Biol Chem. 1985;260(24):12891-4. PMID:2997147
87.	Perlmutter DH, Kay RM, Cole FS, Rossing TH, Van Thiel D, Colten HR. The cellular defect in alpha 1-proteinase inhibitor (alpha 1-PI) deficiency is expressed in human monocytes and in Xenopus oocytes injected with human liver mRNA. Proc Natl Acad Sci U S A. 1985;82(20):6918-21. PMCID:PMC390799 PMID:3876562
88.	Strunk RC, Whitehead AS, Cole FS. Pretranslational regulation of the synthesis of the third component of complement in human mononuclear phagocytes by the lipid A portion of lipopolysaccharide. J Clin Invest. 1985;76(3):985-90. doi:10.1172/JCI112099 PMCID:PMC423963 PMID:3900137
89.	Zannis VI, Cole FS, Jackson CL, Kurnit DM, Karathanasis SK. Distribution of apolipoprotein A-I, C-II, C-III, and E mRNA in fetal human tissues. Time-dependent induction of apolipoprotein E mRNA by cultures of human monocyte-macrophages. Biochemistry. 1985;24(16):4450-5. PMID:3931677
90.	Cole FS, Whitehead AS, Auerbach HS, Lint T, Zeitz HJ, Kilbridge P, Colten HR. The molecular basis for genetic deficiency of the second component of human complement. N Engl J Med. 1985;313(1):11-6. doi:10.1056/NEJM198507043130103 PMID:2582254
91.	Pennington JE, Cole FS, Boerth LW. Intrapulmonary chemotaxins in the normal and in the cyclophosphamide-treated host. Am Rev Respir Dis. 1985;131(6):845-9. doi:10.1164/arrd.1985.131.6.845 PMID:4003935
92.	Cole FS, Auerbach HS, Goldberger G, Colten HR. Tissue-specific pretranslational regulation of complement production in human mononuclear phagocytes. J Immunol. 1985;134(4):2610-6. PMID:3844437
93.	Perlmutter DH, Cole FS, Kilbridge P, Rossing TH, Colten HR. Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages. Proc Natl Acad Sci U S A. 1985;82(3):795-9. PMCID:PMC397133 PMID:3871944
94.	Perlmutter DH, Kay RM, Cole FS, Rossing TH, Van Thiel D, Colten HR. A selective defect in secretion of alpha 1-proteinase inhibitor PiZZ demonstrated in surrogate and primary extrahepatic cell culture. Trans Assoc Am Physicians. 1985;98:47-54. PMID:3879845
95.	Perlmutter DH, Cole FS, Goldberger G, Colten HR. Distinct primary translation products from human liver mRNA give rise to secreted and cell-associated forms of complement protein C2. J Biol Chem. 1984;259(16):10380-5. PMID:6088497
96.	Yin HL, Kwiatkowski DJ, Mole JE, Cole FS. Structure and biosynthesis of cytoplasmic and secreted variants of gelsolin. J Biol Chem. 1984;259(8):5271-6. PMID:6325429
97.	Key L, Carnes D, Cole S, Holtrop M, Bar-Shavit Z, Shapiro F, Arceci R, Steinberg J, Gundberg C, Kahn A. Treatment of congenital osteopetrosis with high-dose calcitriol. N Engl J Med. 1984;310(7):409-15. doi:10.1056/NEJM198402163100701 PMID:6546410
98.	DiPietro MA, Brody BA, Kuban K, Cole FS. Schizencephaly: rare cerebral malformation demonstrated by sonography. AJNR Am J Neuroradiol. 1984;5(2):196-8. PMID:6422720
99.	Winter HS, Cole FS, Huffer LM, Davidson CB, Katz AJ, Edelson PJ. Isolation and characterization of resident macrophages from guinea pig and human intestine. Gastroenterology. 1983;85(2):358-63. PMID:6190701
100.	Cole FS, Matthews WJ Jr, Rossing TH, Gash DJ, Lichtenberg NA, Pennington JE. Complement biosynthesis by human bronchoalveolar macrophages. Clin Immunol Immunopathol. 1983;27(2):153-9. PMID:6553519
101.	Alpert SE, Auerbach HS, Cole FS, Colten HR. Macrophage maturation: differences in complement secretion by marrow, monocyte, and tissue macrophages detected with an improved hemolytic plaque assay. J Immunol. 1983;130(1):102-7. PMID:6336622
102.	Goldberger G, Cole FS, Einstein LP, Auerbach HS, Bitter-Suermann D, Colten HR. Biosynthesis of a structurally abnormal C2 complement protein by macrophages from C2-deficient guinea pigs. J Immunol. 1982;129(5):2061-5. PMID:6922142
103.	Cole FS, Schneeberger EE, Lichtenberg NA, Colten HR. Complement biosynthesis in human breast-milk macrophages and blood monocytes. Immunology. 1982;46(2):429-41. PMCID:PMC1555385 PMID:6919505
104.	Cole FS, Saryan JA, Smith AL. The risk of additional systemic bacterial illness in infants with systemic Streptococcus pneumoniae disease. J Pediatr. 1981;99(1):91-4. PMID:7252672
105.	Beatty DW, Davis AE 3rd, Cole FS, Einstein LP, Colten HR. Biosynthesis of complement by human monocytes. Clin Immunol Immunopathol. 1981;18(3):334-43. PMID:6910430
106.	Cole FS, Matthews WJ Jr, Marino JT, Gash DJ, Colten HR. Control of complement synthesis and secretion in bronchoalveolar and peritoneal macrophages. J Immunol. 1980;125(3):1120-4. PMID:6997377
107.	Cole FS, Brusch JL, Talarico L. A circulating anticoagulant in lepromatous leprosy. Int J Lepr Other Mycobact Dis. 1979;47(2):121-5. PMID:378869
108.	Cole FS, Daum RS, Teller L, Goldmann DA, Smith AL. Effect of ampicillin and chloramphenicol alone and in combination on ampicillin-susceptible and -resistant Haemophilus influenzae type B. Antimicrob Agents Chemother. 1979;15(3):415-9. PMCID:PMC352675 PMID:313752
109.	Schwartz AL, Cole FS, Fiedorek F, Matthews D, Paika I, Frantz ID, Latt SA. Effect of phototherapy on sister chromatid exchange in premature infants. Lancet. 1978;2(8081):157-8. PMID:78359
110.	Cole FS, Todres ID, Shannon DC. Technique for percutaneous cannulation of the radial artery in the newborn infant. J Pediatr. 1978;92(1):105-7. PMID:619050
111.	Askinazi C, Cole FS, Brusch JL. Positive differential heterophile antibody test. Persistence in a symptomatic patient. JAMA. 1976;236(13):1492-3. PMID:183027
112.	Cole FS. A study of neonatal hyperbilirubinemia: The role of the enterohepatic circulation of bilirubin. A thesis submitted in partial fulfillment of the requirements for the degree of Doctor of Medicine to the Departments of Medicine and Pediatrics Yale University School of Medicine, New Haven, Connecticut. 1973.