Stuart Friess, M.D.  friess_s@kids.wustl.edu

Associate Professor of Pediatrics, Critical Care Medicine
Critical Care MedicinePathobiology

phone: 314-286-2799

Research Interests


Dr. Friess has a strong background in translational neurocritical care research with specific training and expertise in large and small animal modelling of acute brain injury. Previous work has included developing neurobehavioral outcome measures in a swine model of head injury and multimodal intracranial monitoring in swine models of traumatic brain injury and cardiac arrest. Currently, Dr. Friess's research is focused on studying the effects of delayed secondary insults on white matter injury following traumatic brain injury.

Education

  • B.S., Brown University 1995
  • M.D., Mount Sinai School of Medicine of NYU 1999

Training

  • Internship and Residency, Pediatrics, Mount Sinai Hospital, NY, NY1999 - 2002
  • Chief Resident, Mount Sinai Hospital 2002 - 2003
  • Fellow , The Children’s Hospital of Philadelphia2003 - 2006

Licensure and Board Certification

  • PA, 
  • NY, 
  • MO, 
  • American Board of Pediatrics (renewed 2012)2003
  • American Board of Pediatrics, Sub-board of Pediatric Critical Care Medicine2006

Honors

  • Sigma Xi Honor Society1994
  • Tau Beta Pi Engineering Honor Society1995
  • Mount Sinai School of Medicine Dr. Morris Bender Family Award in the Neurosciences1997
  • Alpha Omega Alpha Honor Society1998
  • Mount Sinai School of Medicine Bela Schick Pediatric Society Prize for Excellence in Pediatrics1999
  • NIH Pediatric Research Loan Repayment Program recipient2006 - 2014
  • Society of Critical Care Medicine CPR Specialty Award2014
  • Society of Critical Care Medicine Pediatrics Section Travel Grant2014
  • Member, Society for Pediatric Research2015 - Pres
  • Star Research Presentation Award, Society of Critical Care Medicine Annual Congress2016

Selected Publications view all (10)


Publication Co-Authors

  1. Parikh U, Williams M, Jacobs A, Pineda JA, Brody DL, Friess SH. Delayed Hypoxemia Following Traumatic Brain Injury Exacerbates White Matter Injury. J Neuropathol Exp Neurol. 2016. PMID:27288907  
  2. Ostendorf AP, Hartman ME, Friess SH. Early Electroencephalographic Findings Correlate With Neurologic Outcome in Children Following Cardiac Arrest. Pediatr Crit Care Med. 2016;17(7):667-76. PMID:27164188  
  3. Naim MY, Sutton RM, Friess SH, Bratinov G, Bhalala U, Kilbaugh TJ, Lampe JW, Nadkarni VM, Becker LB, Berg RA. Blood Pressure- and Coronary Perfusion Pressure-Targeted Cardiopulmonary Resuscitation Improves 24-Hour Survival From Ventricular Fibrillation Cardiac Arrest. Crit Care Med. 2016;44(11):e1111-e1117. PMCID:PMC5069077  PMID:27414479  
  4. Yang C, Friess SH, Dehner LP. Hepatic Mucormycosis Mimicking Veno-occlusive Disease: Report of a Case and Review of the Literature. Pediatr Dev Pathol. 2015. doi:10.2350/15-06-1661-CR.1  PMID:26366930  
  5. Friess SH, Lapidus JB, Brody DL. Decompressive craniectomy reduces white matter injury after controlled cortical impact in mice. J Neurotrauma. 2015;32(11):791-800. doi:10.1089/neu.2014.3564  PMID:25557588  
  6. Friess SH, Bruins B, Kilbaugh TJ, Smith C, Margulies SS. Differing effects when using phenylephrine and norepinephrine to augment cerebral blood flow after traumatic brain injury in the immature brain. J Neurotrauma. 2015;32(4):237-43. doi:10.1089/neu.2014.3468  PMCID:PMC4321769  PMID:25072522  
  7. Sutton RM, Friess SH, Naim MY, Lampe JW, Bratinov G, Weiland TR 3rd, Garuccio M, Nadkarni VM, Becker LB, Berg RA. Patient-centric blood pressure-targeted cardiopulmonary resuscitation improves survival from cardiac arrest. Am J Respir Crit Care Med. 2014;190(11):1255-62. doi:10.1164/rccm.201407-1343OC  PMCID:PMC4315818  PMID:25321490  
  8. Topjian AA, Stuart A, Pabalan AA, Clair A, Kilbaugh TJ, Abend NS, Storm PB, Berg RA, Huh JW, Friess SH. Greater fluctuations in serum sodium levels are associated with increased mortality in children with externalized ventriculostomy drains in a PICU. Pediatr Crit Care Med. 2014;15(9):846-55. doi:10.1097/PCC.0000000000000223  PMCID:PMC4221432  PMID:25137551  
  9. Topjian AA, Stuart A, Pabalan AA, Clair A, Kilbaugh TJ, Abend NS, Berg RA, Heuer GG, Storm PB Jr, Huh JW, Friess SH. Risk factors associated with infections and need for permanent cerebrospinal fluid diversion in pediatric intensive care patients with externalized ventricular drains. Neurocrit Care. 2014;21(2):294-9. doi:10.1007/s12028-013-9946-7  PMCID:PMC4133323  PMID:24522759  
  10. Milner E, Holtzman JC, Friess S, Hartman RE, Brody DL, Han BH, Zipfel GJ. Endovascular perforation subarachnoid hemorrhage fails to cause Morris water maze deficits in the mouse. J Cereb Blood Flow Metab. 2014;34(9). doi:10.1038/jcbfm.2014.108  PMCID:PMC4158664  PMID:24938403