Dorothy Katherine Grange, M.D.  grange_d@kids.wustl.edu

Professor of Pediatrics, Division of Genetics and Genomic Medicine
Genetics and Genomic MedicinePatient Oriented Research Unit

phone: (314) 454-6093

Education

  • BA, Cum Laude, Mount Holyoke College1980
  • MD, University of Florida College of Medicine1982

Training

  • Intern, University of Florida1981 - 1982
  • Intern and Resident, University of Wisconsin1982 - 1985
  • Resident, University of Wisconsin1985 - 1986
  • Fellowship Program, National Institutes of Health1986 - 1989

Licensure and Board Certification

  • WI, 1981
  • National Board of Medical Examiners 1982
  • MD, 1986
  • American Academy of Pediatrics 1987
  • MO, 1989
  • Clinical Genetics, American Board of Medical Genetics 1990
  • IL, 2002
  • Medical Biochemical Genetics, American Board of Medical Genetics 2009

Honors

  • Dean Mitchell Baker Medical Student Award for Pediatric Cardiology1981
  • Outstanding Teacher Award - Subspecialty, Department of Pediatrics, Washington University School of Medicine2008 - 2009
  • Distinguished Clinician Award, Washington University School of Medicine2015

Selected Publications view all (96)


1.
A Recurrent Mosaic Mutation in SMO, Encoding the Hedgehog Signal Transducer Smoothened, Is the Major Cause of Curry-Jones Syndrome. Am J Hum Genet. 2016;98(6):1256-65. doi:10.1016/j.ajhg.2016.04.007  PMID:27236920 
2.
KATP channel gain-of-function leads to increased myocardial L-type Ca2+ current and contractility in Cantu syndrome. Proc Natl Acad Sci U S A. 2016. doi:10.1073/pnas.1606465113  PMID:27247394 
3.
Clinical and radiographic delineation of bent bone dysplasia-FGFR2 type or bent bone dysplasia with distinctive clavicles and angel-shaped phalanges. Am J Med Genet A. 2016. doi:10.1002/ajmg.a.37772  PMID:27240702 
4.
A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex. Am J Hum Genet. 2016;98(5):909-18. doi:10.1016/j.ajhg.2016.03.014  PMID:27132593 
5.
Dermatologic findings of focal dermal hypoplasia (Goltz syndrome). Am J Med Genet C Semin Med Genet. 2016;172(1):44-51. doi:10.1002/ajmg.c.31472  PMID:26858134 
6.
Multigenerational autosomal dominant inheritance of 5p chromosomal deletions. Am J Med Genet A. 2016;170(3):583-93. doi:10.1002/ajmg.a.37445  PMID:26601658 
7.
Myhre syndrome: Clinical features and restrictive cardiopulmonary complications. Am J Med Genet A. 2015;167(12):2893-901. doi:10.1002/ajmg.a.37273  PMID:26420300 
8.
Electrophysiologic consequences of KATP gain of function in the heart: Conduction abnormalities in Cantu syndrome. Heart Rhythm. 2015. doi:10.1016/j.hrthm.2015.06.042  PMID:26142302 
9.
Fabry disease in infancy and early childhood: a systematic literature review Genet Med. 2015;17(5):323-30. PMID: 25232851  
10.
Brainstem disconnection: two additional patients and expansion of the phenotype. Neuropediatrics. 2015;46(2):139-44. doi:10.1055/s-0034-1544127  PMID:25671339