Research Interests


Dr. Hayashi is Director of the Division of Pediatric Hematology/Oncology and an attending physician in Hematology/Oncology and General Pediatrics at St. Louis Children’s Hospital. Dr. Hayashi's research interest primarily focuses on issues regarding the long term effects of cancer therapy. His efforts examine the nature and spectrum of clinical conditions that effect childhood cancer survivors with the goal of developing interventions that will improve the outlook of this patient population. He is involved in both institutional and national efforts to gain insight in this rapidly evolving area of investigation and he also directs The Late Effects Clinic at St. Louis Children’s Hospital providing comprehensive care for patients afflicted with a broad scope of conditions.Dr. Hayashi's clinical interests also include bone marrow transplantation, Non-Hodgkin's Lymphoma and post-transplant lymphoproliferative disease (PTLD). He is actively involved in national trials advancing the treatment of patients in these areas.

Education

  • B.S., Departmental Honors, Stanford University1982
  • M.D., Washington Unversity School of Medicine1986

Training

  • Intern in Pediatrics, St. Louis Chiildren's Hospital1986 - 1987
  • Resident in Pediatrics , St. Louis Children's Hospital1987 - 1989
  • Fellowship in Pediatric Hematology/Oncology, The Johns Hopkins School of Medicine 1989 - 1992

Licensure and Board Certification

  • American Board of Pediatrics1991
  • Pediatric Hematology/Oncology1992
  • MO, Missouri Medical Licensure1994

Honors

  • Departmental Honors, Department of Biology, Stanford University, Stanford California1982
  • Child Health Research Center Award1990 - 1992
  • Physicain Scientist Award1992 - 1997
  • Castle Connolly's America's Top Doctors in Cancer2005 - Pres
  • Castle Connolly's America's Top Doctors2006 - Pres
  • Legacy Award, National Children's Cancer Society2006
  • Medical Excellence Award, National Childrens Cancer Society2013

Selected Publications view all (10)


Publication Co-Authors

  1. Mohrmann C, Armer J, Hayashi RJ. Challenges Evaluating Chemotherapy-Induced Peripheral Neuropathy in Childhood Cancer Survivors: Which Instrument Should Nurses Use? J Pediatr Oncol Nurs. 2016. doi:10.1177/1043454216651016  PMID:27251891  
  2. Madden LM, Hayashi RJ, Chan KW, Pulsipher MA, Douglas D, Hale GA, Chaudhury S, Haut P, Kasow KA, Gilman A, Murray LM, Shenoy S. Long-Term Follow-Up after Reduced-Intensity Conditioning and Stem Cell Transplantation for Childhood Nonmalignant Disorders. Biol Blood Marrow Transplant. 2016. doi:10.1016/j.bbmt.2016.04.025  PMID:27164064  
  3. Stieglitz E, Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T, Esquivel E, Yu A, Seepo S, Olsen SR, Rosenberg M, Archambeault SL, Abusin G, Beckman K, Brown PA, Briones M, Carcamo B, Cooper T, Dahl GV, Emanuel PD, Fluchel MN, Goyal RK, Hayashi RJ, Hitzler J, Hugge C, Liu YL, Messinger YH, Mahoney DH Jr, Monteleone P, Nemecek ER, Roehrs PA, Schore RJ, Stine KC, Takemoto CM, Toretsky JA, Costello JF, Olshen AB, Stewart C, Li Y, Ma J, Gerbing RB, Alonzo TA, Getz G, Gruber TA, Golub TR, Stegmaier K, Loh ML. The genomic landscape of juvenile myelomonocytic leukemia. Nat Genet. 2015. doi:10.1038/ng.3400  PMID:26457647  
  4. King AA, Kamani N, Bunin N, Sahdev I, Brochstein J, Hayashi RJ, Grimley M, Abraham A, Dioguardi J, Chan KW, Douglas D, Adams R, Andreansky M, Anderson E, Gilman A, Chaudhury S, Yu L, Dalal J, Hale G, Cuvelier G, Jain A, Krajewski J, Gillio A, Kasow KA, Delgado D, Hanson E, Murray L, Shenoy S. Successful matched sibling donor marrow transplantation following reduced intensity conditioning in children with hemoglobinopathies. Am J Hematol. 2015. doi:10.1002/ajh.24183  PMID:26348869  
  5. Burke MJ, Verneris MR, Le Rademacher J, He W, Abdel-Azim H, Abraham AA, Auletta JJ, Ayas M, Brown VI, Cairo MS, Chan KW, Diaz Perez MA, Dvorak CC, Egeler RM, Eldjerou L, Frangoul H, Guilcher GM, Hayashi RJ, Ibrahim A, Kasow KA, Leung WH, Olsson RF, Pulsipher MA, Shah N, Shah NN, Thiel E, Talano JA, Kitko CL. Transplant Outcomes for Children with T Cell Acute Lymphoblastic Leukemia in Second Remission: A Report from the Center for International Blood and Marrow Transplant Research. Biol Blood Marrow Transplant. 2015. doi:10.1016/j.bbmt.2015.08.023  PMID:26327632  
  6. Satwani P, Ahn KW, Carreras J, Abdel-Azim H, Cairo MS, Cashen A, Chen AI, Cohen JB, Costa LJ, Dandoy C, Fenske TS, Freytes CO, Ganguly S, Gale RP, Ghosh N, Hertzberg MS, Hayashi RJ, Kamble RT, Kanate AS, Keating A, Kharfan-Dabaja MA, Lazarus HM, Marks DI, Nishihori T, Olsson RF, Prestidge TD, Rolon JM, Savani BN, Vose JM, Wood WA, Inwards DJ, Bachanova V, Smith SM, Maloney DG, Sureda A, Hamadani M. A prognostic model predicting autologous transplantation outcomes in children, adolescents and young adults with Hodgkin lymphoma. Bone Marrow Transplant. 2015. doi:10.1038/bmt.2015.177  PMID:26237164  
  7. Inamoto Y, Flowers ME, Wang T, Urbano-Ispizua A, Hemmer MT, Cutler CS, Couriel DR, Alousi AM, Antin JH, Gale RP, Gupta V, Hamilton BK, Kharfan-Dabaja MA, Marks DI, Ringdén OT, Socié G, Solh MM, Akpek G, Cairo MS, Chao NJ, Hayashi RJ, Nishihori T, Reshef R, Saad A, Shah A, Teshima T, Tallman MS, Wirk B, Spellman SR, Arora M, Martin PJ. Tacrolimus versus Cyclosporine after Hematopoietic Cell Transplantation for Acquired Aplastic Anemia. Biol Blood Marrow Transplant. 2015. doi:10.1016/j.bbmt.2015.05.023  PMID:26033280  
  8. Urbano-Ispizua A, Pavletic SZ, Flowers ME, Klein JP, Zhang MJ, Carreras J, Montoto S, Perales MA, Aljurf MD, Akpek G, Bredeson CN, Costa LJ, Dandoy C, Freytes CO, Fung HC, Gale RP, Gibson J, Hamadani M, Hayashi RJ, Inamoto Y, Inwards DJ, Lazarus HM, Maloney DG, Martino R, Munker R, Nishihori T, Olsson RF, Rizzieri DA, Reshef R, Saad A, Savani BN, Schouten HC, Smith SM, Socié G, Wirk B, Yu LC, Saber W. The Impact of Graft-versus-Host Disease on the Relapse Rate in Patients with Lymphoma Depends on the Histological Subtype and the Intensity of the Conditioning Regimen. Biol Blood Marrow Transplant. 2015. doi:10.1016/j.bbmt.2015.05.010  PMID:25981509  
  9. Mohrmann C, Henry J, Hauff M, Hayashi RJ. Neurocognitive outcomes and school performance in solid tumor cancer survivors lacking therapy to the central nervous system. J Pers Med. 2015;5(2):83-90. doi:10.3390/jpm5020083  PMID:25867598  
  10. Kothari A, Ngwube A, Hayashi R, Murray L, Davis J, Haut P, Loechelt BJ, Shenoy S. Hematopoietic Cell Transplantation Using Reduced-Intensity Conditioning Is Successful in Children with Hematologic Cytopenias of Genetic Origin. Biol Blood Marrow Transplant. 2015. doi:10.1016/j.bbmt.2015.03.019  PMID:25840334