Patrick Y. Jay, M.D., Ph.D.

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Associate Professor of Pediatrics, Genetics
Associate Professor of Pediatrics, Cardiology



  • BS, with honors and distinction, Stanford University1987
  • MD, Washington University School of Medicine1995
  • PhD, Washington University1995


  • Pediatric Resident, Children's Hospital1995 - 1997
  • Pediatric Cardiology Fellow, Children's Hospital1997 - 2001
  • Postdoctoral Research, Harvard Medical School1999 - 2004

Licensure and Board Certification

  • MA, Massachusetts medical license, 2000 - 2005
  • American Board of Pediatrics, 2001 - 2007
  • American Board of Pediatrics, Pediatric Cardiology, 2002 - 2019
  • MO, Missouri, Physician License, 2004 - Pres
  • IL, Illinois medical license, 2008 - 2011


  • Kodak Scholar1985 - 1987
  • Spencer T. and Ann W. Olin Medical Scientist Fellow1994
  • Lee C. Falke Memorial Prize in Biophysics and Biomedical Engineering1995
  • Richard D. Rowe Award in Perinatal Cardiology2004
  • Scholar, Child Health Research Center Scholar in Developmental Biology2004 - 2007
  • Chancellor's Hartwell Prize for Innovative Research2005
  • American Heart Association Established Investigator2013 - 2017

Selected Publications view all (38)

Publication Co-Authors

The maternal-age-associated risk of congenital heart disease is modifiable. Nature. 2015;520:230-3. doi:10.1038/nature14361  PMCID:PMC4393370  PMID:25830876 
Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model. Sci Rep. 2015;5:7826. doi:10.1038/srep07826  PMID:25591392 
Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret. Mol Cell Endocrinol. 2015;399:122-30. doi:10.1016/j.mce.2014.09.029  PMCID:PMC4262703  PMID:25289806 
A single misstep in cardiac development explains the co-occurrence of tetralogy of fallot and complete atrioventricular septal defect in Down syndrome. J Pediatr. 2014;165:194-6. doi:10.1016/j.jpeds.2014.02.065  PMCID:PMC4074567  PMID:24721467 
Tissue Doppler septal Tei index indicates severity of illness in pediatric patients with congestive heart failure. Pediatr Cardiol. 2014;35:411-8. doi:10.1007/s00246-013-0794-1  PMID:24061276 
Ex vivo, microelectrode analysis of conduction through the AV node of wild-type and Nkx2-5 mutant mouse hearts as guided by a Cx40-eGFP transgenic reporter. Physiol Rep. 2014;2:e00285. doi:10.14814/phy2.285  PMCID:PMC4001877  PMID:24771692 
Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. Gastroenterology. 2014;146:157-65. doi:10.1053/j.gastro.2013.10.008  PMCID:PMC3889663  PMID:24120474 
Association of genes with physiological functions by comparative analysis of pooled expression microarray data. Physiol Genomics. 2013;45:69-78. doi:10.1152/physiolgenomics.00116.2012  PMCID:PMC3546411  PMID:23170034 
Saxagliptin Improves Glucose Tolerance but not Survival in a Murine Model of Dilated Cardiomyopathy. Cardiovasc Endocrinol. 2012;1:74-82. doi:10.1097/XCE.0b013e32835bfb24  PMCID:PMC3686315  PMID:23795310 
Complex trait analysis of ventricular septal defects caused by Nkx2-5 mutation. Circ Cardiovasc Genet. 2012;5:293-300. doi:10.1161/CIRCGENETICS.111.961136  PMCID:PMC3521568  PMID:22534315 
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