My research interest encompasses the safe and effective delivery of healthcare to children. Children are amongst the most vulnerable users of the health care system, frequently unable to state when they are experiencing a change in their clinical status or an alteration in a standard of care. We have participated in several multicenter trials to delineate ways to best deliver care to children, including a study to investigate trigger tools for unexpected events. We are currently participating in a multicenter trial to evaluate sedation practices in children. Additionally, our Pediatric Intensive Care Unit studied and published a novel error reporting tool. Our Rapid Response Team, launched in 2008, has been associated with a fifty percent reduction in our code rate and a substantial impact on hospital mortality. We have recently implemented the Pediatric Early Warning System (PEWS) with the expectation it will provide further improvement in outcome.