Pediatric Research

Stephanie A. Fritz, M.D., M.S.C.I. fritz.s@wustl.edu

Associate Professor of Pediatrics, Infectious Diseases

View my lab

Infectious Diseases

phone: (314) 454-6050

Research Interests

Dr. Fritz's research interests are in the epidemiology, treatment, and prevention of pediatric methicillin-resistant Staphylococcus aureus infections.

Education

BS, University of Wisconsin, 1997
MD, Medical College of Wisconsin, 2001
MSCI, Washington University School of Medicine, 2008

Training

Intern/Resident in Pediatrics, Children's Hospital of Wisconsin, 2001 - 2004
Fellow, Pediatric Infectious Diseases, Washington University , 2004 - 2007

Licensure and Board Certification

2003 - PresWI, Physician and Surgeon
2004 - PresMO, Physician and Surgeon
2004 - 2024American Board of Pediatrics (ABP)
2007 - 2017ABP Sub-board of Pediatric Infectious Diseases

Honors

Phi Eta Sigma Honor Society, 1994 - 1997
Elmbrook Memorial Hospital John O. Grade, M.D. Scholarship, 1997
University of Wisconsin-Madison: Graduated with Distinction, 1997
Watertown Memorial Hospital Cynthia Kolasinski Scholarship, 1999 - 2000
Wisconsin State Medical Society Foundation Scholarship, 2000
Scholar, Mentored Training Program in Clinical Investigation, Washington University School of Medicine, St. Louis, MO, 2005 - 2008
National Institutes of Health Loan Repayment Program Award, 2006 - 2009
Infectious Diseases Society of America/ National Foundation for Infectious Diseases Pfizer Fellowship in Clinical Diseases Award, 2007
Faculty Scholar Award, Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital, 2012
Young Investigator Award, Pediatric Infectious Diseases Society, 2012
Featured Member, Society for Pediatric Research, 2014
Resident/Fellow Alumni Achievement Award, Washington University Medical Center Alumni Association, 2018

Selected Publications view all (43)

Publication Co-Authors

Indi Trehan, MD, MPH, DTM&H

Gregory A. Storch, M.D.

Duha Al-Zubeidi

Phillip I. Tarr, M.D.

David A. Hunstad, M.D.

Kristine Wylie, Ph.D.

Barbara B. Warner, M.D., MSc

Rachel C. Orscheln, M.D.

Alexis M. Elward, M.D., M.P.H.

Jane M. Garbutt, M.D.

Todd N. Wylie

Reich, Patrick

Victoria Fraser

S. Celeste Morley, M.D., Ph.D.

1.	Morelli JJ, Hogan PG, Sullivan ML, Muenks CE, Wang JW, Thompson RM, Burnham CA, Fritz SA. Antimicrobial Susceptibility Profiles of Staphylococcus aureus Isolates Recovered from Humans, Environmental Surfaces, and Companion Animals in Households of Children with Community-Onset Methicillin-Resistant S. aureus Infections. Antimicrob Agents Chemother. 2015;59(10):6634-7. doi:10.1128/AAC.01492-15 PMCID:PMC4576049 PMID:26248385
2.	Rodriguez M, Hogan PG, Satola SW, Crispell E, Wylie T, Gao H, Sodergren E, Weinstock GM, Burnham CA, Fritz SA. Discriminatory Indices of Typing Methods for Epidemiologic Analysis of Contemporary Staphylococcus aureus Strains. Medicine (Baltimore). 2015;94(37):e1534. doi:10.1097/MD.0000000000001534 PMCID:PMC4635816 PMID:26376402
3.	Creech CB, Al-Zubeidi DN, Fritz SA. Prevention of Recurrent Staphylococcal Skin Infections. Infect Dis Clin North Am. 2015;29(3):429-64. doi:10.1016/j.idc.2015.05.007 PMCID:PMC4552962 PMID:26311356
4.	Wang JW, Hogan PG, Hunstad DA, Fritz SA. Vitamin D sufficiency and Staphylococcus aureus infection in children. Pediatr Infect Dis J. 2015;34(5):544-5. doi:10.1097/INF.0000000000000667 PMCID:PMC4400212 PMID:25860535
5.	Hogan PG, Burnham CA, Singh LN, Patrick CE, Lukas JC, Wang JW, Fraser VJ, Fritz SA. Evaluation of Environmental Sampling Methods for Detection of Staphylococcus aureus on Fomites. Ann Public Health Res. 2015;2(1). PMCID:PMC4399720 PMID:25893222
6.	Fritz SA, Hogan PG, Singh LN, Thompson RM, Wallace MA, Whitney K, Al-Zubeidi D, Burnham CA, Fraser VJ. Contamination of environmental surfaces with Staphylococcus aureus in households with children infected with methicillin-resistant S aureus. JAMA Pediatr. 2014;168(11):1030-8. doi:10.1001/jamapediatrics.2014.1218 PMCID:PMC4219733 PMID:25200331
7.	Al-Zubeidi D, Burnham CA, Hogan PG, Collins R, Hunstad DA, Fritz SA. Molecular Epidemiology of Recurrent Cutaneous Methicillin-Resistant Staphylococcus aureus Infections in Children. J Pediatric Infect Dis Soc. 2014;3(3):261-264. doi:10.1093/jpids/pit046 PMCID:PMC4381745 PMID:25844165
8.	Gurnee EA, Ndao IM, McGhee JE, Warner BB, Tarr PI, Fritz SA, Burnham CA. Fecal carriage of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus in healthy children. Antimicrob Agents Chemother. 2014;58(2):1261-2. doi:10.1128/AAC.02466-13 PMCID:PMC3910844 PMID:24277049
9.	Rodriguez M, Hogan PG, Burnham CA, Fritz SA. Molecular epidemiology of Staphylococcus aureus in households of children with community-associated S aureus skin and soft tissue infections. J Pediatr. 2014;164(1):105-11. doi:10.1016/j.jpeds.2013.08.072 PMCID:PMC3921902 PMID:24128648
10.	Al-Zubeidi D, Hogan PG, Boyle M, Burnham CA, Fritz SA. Molecular epidemiology of methicillin-resistant Staphylococcus aureus isolated in serial cultures from the respiratory tract of children with cystic fibrosis. Pediatr Infect Dis J. 2013. doi:10.1097/INF.0000000000000204 PMID:24220228

1.	Briscoe C, Reich PJ, Fritz SA, Coughlin CC.. Staphylococcus aureus antibiotic susceptibility patterns in pediatric atopic dermatitis. Pediatr Dermaol. 2019.
2.	Hogan PG, Mork RL, Boyle MG, Muenks CE, Morelli JJ, Thompson RM, Sullivan ML, Gehlert SJ, Merlo JR, McKenzie MG, Bubeck Wardenburg J, Rzhetsky A, Burnham CD, Fritz SA. Interplay of personal, pet, and environmental colonization in households affected by community-associated methicillin-resistant Staphylococcus aureus. Journal of Infection. 2019;78(3):200-207. doi:10.1016/j.jinf.2018.11.006 PMCID: PMC6408279 PMID:30503843
3.	Liang SY, Jansson DR, Hogan PG, Raclin TW, Sullivan ML, Muenks CE, Munigala S, House SL, Fritz SA.. Emergency department environmental contamination with methicillin-resistant Staphylococcus aureus following care of colonized patients Ann Emerg Med. 2019. doi:10.1016/j.annemergmed.2018.12.014 PMID:30732980
4.	Parrish KL, Wylie KM, Reich PJ, Hogan PG, Wylie TN, Kennedy CR, Lainhart W, Hunstad DA, Burnham CD, Fritz SA.. Carriage of the Toxic Shock Syndrome Toxin Gene by Contemporary Community-Associated Staphylococcus aureus Isolates. J Pediatric Infect Dis Soc.. 2018. doi:10.1093/jpids/piy098 PMID:30285124
5.	Parrish KL, Hogan PG, Clemons A, Fritz SA.. Spatial relationships among public places frequented by families plagued by methicillin-resistant Staphylococcus aureus. BMC Res Notes. 2018;11(1):692. doi:10.1186/s13104-018-3797-4 PMCID:PMC6167789 PMID:30285824
6.	Muenks CE, Hogan PG, Burnham CD, Fritz SA. Comparing the yield of Staphylococcus aureus recovery with static versus agitated broth incubation Journal of Pathogens. 2018;Article ID 1462671. doi:10.1155/2018/1462671 PMCID:PMC6083490 PMID:30147954
7.	Mork RL, Hogan PG, Muenks CE, Boyle MG, Thompson RM, Morelli JJ, Sullivan ML, Gehlert SJ, Ross DG, Yn A, Bubeck Wardenburg J, Rzhetsky A, Burnham CD, Fritz SA. Comprehensive modeling reveals proximity, seasonality, and hygiene practices as key determinants of MRSA colonization in exposed households Pediatr Res. 2018. PMCID:PMC6294678 PMID:30135590
8.	Muenks CE, Sewell WC, Hogan PG, Thompson, RM, Ross DG, Wang JW, Morelli JJ, Gehlert SJ, Fritz SA. Methicillin-resistant Staphylococcus aureus: Its effects are more than skin deep J Pediatr. 2018;199:158-165. doi:10.1016/j.jpeds.2018.04.002 PMCID: PMC6063792 PMID:29759849
9.	Hogan PG, Rodriguez M, Spenner AM, Brenneisen JM, Boyle MG, Sullivan ML, Fritz SA. Impact of systemic antibiotics on Staphylococcus aureus colonization and recurrent skin infection Clin Infect Dis. 2017. doi:10.1093/cid/cix754 PMCID:PMC5850557 PMID:29020285
10.	Daum RS, Miller LG, Immergluck L, Fritz S, Creech CB, Young D, Kumar N, Downing M, Pettibone S, Hoagland R, Eells SJ, Boyle MG, Parker TC, Chambers HF. A placebo-controlled trial of antibiotics for smaller skin abscesses. New Engl J Med . 2017;376:2545-2555. PMID:28657870
11.	McFarland M, Szasz TP, Zhou JY, Motley K, Sivapalan JS, Isaacson-Schmid M, Todd EM, Hogan PG, Fritz SA, Burnham CD, Hoffmann S, Morley SC. Colonization with 19F and other pneumococcal conjugate vaccine serotypes in children in St. Louis, Missouri, USA. Vaccine. 2017;35(34):4389-4395. PMID:28687405
12.	Burnham CA, Hogan PG, Wallace MA, Deych E, Shannon W, Warren DK, Fritz SA. Topical Decolonization Does Not Eradicate the Skin Microbiota of Community-Dwelling or Hospitalized Adults. Antimicrob Agents Chemother. 2016;60(12):7303-7312. PMCID:PMC5119011 PMID:27671074
13.	Muenks CE, Hogan PG, Wang JW, Eisenstein KA, Burnham CA, Fritz SA. Diversity of Staphylococcus aureus strains colonizing various niches of the human body. J Infect 2016. 2016;72:698-705. PMID:27045982
14.	Reich PJ, Boyle MG, Hogan PG, Johnson AJ, Wallace MA, Elward AM, Warner BB, Burnham CA, Fritz SA. Emergence of community-associated methicillin-resistant Staphylococcus aureus strains in the neonatal intensive care unit: an infection prevention and patient safety challenge. Clin Microbiol Infect . 2016;22:645.e1-645.e8. PMCID:PMC4987169 PMID:27126609
15.	Morelli JJ, Hogan PG, Sullivan ML, Muenks CE, Wang JW, Thompson RM, Burnham CA, Fritz SA. Antimicrobial Susceptibility Profiles of Staphylococcus aureus Isolates Recovered from Humans, Environmental Surfaces, and Companion Animals in Households of Children with Community-Onset Methicillin-Resistant S. aureus Infections. Antimicrob Agents Chemother. 2015;59(10):6634-7. doi:10.1128/AAC.01492-15 PMCID:PMC4576049 PMID:26248385
16.	Rodriguez M, Hogan PG, Satola SW, Crispell E, Wylie T, Gao H, Sodergren E, Weinstock GM, Burnham CA, Fritz SA. Discriminatory Indices of Typing Methods for Epidemiologic Analysis of Contemporary Staphylococcus aureus Strains. Medicine (Baltimore). 2015;94(37):e1534. doi:10.1097/MD.0000000000001534 PMCID:PMC4635816 PMID:26376402
17.	Creech CB, Al-Zubeidi DN, Fritz SA. Prevention of Recurrent Staphylococcal Skin Infections. Infect Dis Clin North Am. 2015;29(3):429-64. doi:10.1016/j.idc.2015.05.007 PMCID:PMC4552962 PMID:26311356
18.	Wang JW, Hogan PG, Hunstad DA, Fritz SA. Vitamin D sufficiency and Staphylococcus aureus infection in children. Pediatr Infect Dis J. 2015;34(5):544-5. doi:10.1097/INF.0000000000000667 PMCID:PMC4400212 PMID:25860535
19.	Hogan PG, Burnham CA, Singh LN, Patrick CE, Lukas JC, Wang JW, Fraser VJ, Fritz SA. Evaluation of Environmental Sampling Methods for Detection of Staphylococcus aureus on Fomites. Ann Public Health Res. 2015;2(1). PMCID:PMC4399720 PMID:25893222
20.	Land AD, Hogan P, Fritz S, Levin P. Phenotypic variation is almost entirely independent of the host-pathogen relationship in clinical isolates of S. aureus. PLoS ONE. 2015;10(6):e0129670.
21.	Fritz SA, Hogan PG, Singh LN, Thompson RM, Wallace MA, Whitney K, Al-Zubeidi D, Burnham CA, Fraser VJ. Contamination of environmental surfaces with Staphylococcus aureus in households with children infected with methicillin-resistant S aureus. JAMA Pediatr. 2014;168(11):1030-8. doi:10.1001/jamapediatrics.2014.1218 PMCID:PMC4219733 PMID:25200331
22.	Al-Zubeidi D, Burnham CA, Hogan PG, Collins R, Hunstad DA, Fritz SA. Molecular Epidemiology of Recurrent Cutaneous Methicillin-Resistant Staphylococcus aureus Infections in Children. J Pediatric Infect Dis Soc. 2014;3(3):261-264. doi:10.1093/jpids/pit046 PMCID:PMC4381745 PMID:25844165
23.	Gurnee EA, Ndao IM, McGhee JE, Warner BB, Tarr PI, Fritz SA, Burnham CA. Fecal carriage of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus in healthy children. Antimicrob Agents Chemother. 2014;58(2):1261-2. doi:10.1128/AAC.02466-13 PMCID:PMC3910844 PMID:24277049
24.	Rodriguez M, Hogan PG, Burnham CA, Fritz SA. Molecular epidemiology of Staphylococcus aureus in households of children with community-associated S aureus skin and soft tissue infections. J Pediatr. 2014;164(1):105-11. doi:10.1016/j.jpeds.2013.08.072 PMCID:PMC3921902 PMID:24128648
25.	Al-Zubeidi D, Hogan PG, Boyle M, Burnham CA, Fritz SA. Molecular epidemiology of methicillin-resistant Staphylococcus aureus isolated in serial cultures from the respiratory tract of children with cystic fibrosis. Pediatr Infect Dis J. 2013. doi:10.1097/INF.0000000000000204 PMID:24220228
26.	Fritz SA, Tiemann KM, Hogan PG, Epplin EK, Rodriguez M, Al-Zubeidi DN, Bubeck Wardenburg J, Hunstad DA. A serologic correlate of protective immunity against community-onset Staphylococcus aureus infection. Clin Infect Dis. 2013;56(11):1554-61. doi:10.1093/cid/cit123 PMCID:PMC3641868 PMID:23446627
27.	Rodriguez M, Hogan PG, Krauss M, Warren DK, Fritz SA. Measurement and Impact of Staphylococcus aureus Colonization Pressure in Households. J Pediatric Infect Dis Soc. 2013;2(2):147-154. doi:10.1093/jpids/pit002 PMCID:PMC3665327 PMID:23717786
28.	Fritz SA, Hogan PG, Camins BC, Ainsworth AJ, Patrick C, Martin MS, Krauss MJ, Rodriguez M, Burnham CA. Mupirocin and chlorhexidine resistance in Staphylococcus aureus in patients with community-onset skin and soft tissue infections. Antimicrob Agents Chemother. 2013;57(1):559-68. doi:10.1128/AAC.01633-12 PMCID:PMC3535967 PMID:23147738
29.	El Feghaly RE, Stamm JE, Fritz SA, Burnham CA. Presence of the bla(Z) beta-lactamase gene in isolates of Staphylococcus aureus that appear penicillin susceptible by conventional phenotypic methods. Diagn Microbiol Infect Dis. 2012;74(4):388-93. doi:10.1016/j.diagmicrobio.2012.07.013 PMID:22959917
30.	Fritz SA, Long M, Gaebelein CJ, Martin MS, Hogan PG, Yetter J. Practices and procedures to prevent the transmission of skin and soft tissue infections in high school athletes. J Sch Nurs. 2012;28(5):389-96. doi:10.1177/1059840512442899 PMID:22472636
31.	Fritz SA, Hogan PG, Hayek G, Eisenstein KA, Rodriguez M, Krauss M, Garbutt J, Fraser VJ. Staphylococcus aureus colonization in children with community-associated Staphylococcus aureus skin infections and their household contacts. Arch Pediatr Adolesc Med. 2012;166(6):551-7. doi:10.1001/archpediatrics.2011.900 PMCID:PMC3596005 PMID:22665030
32.	Fritz SA, Hogan PG, Hayek G, Eisenstein KA, Rodriguez M, Epplin EK, Garbutt J, Fraser VJ. Household versus individual approaches to eradication of community-associated Staphylococcus aureus in children: a randomized trial. Clin Infect Dis. 2012;54(6):743-51. doi:10.1093/cid/cir919 PMCID:PMC3284213 PMID:22198793
33.	Fritz SA, Camins BC, Dukes J, Storch GA. Reply to Herigon and Newland: the role of intention-to-treat analyses in randomized trials Infect Control Hosp Epidemiol . 2012;33(208):210.
34.	Fritz SA, Camins BC, Eisenstein KA, Fritz JM, Epplin EK, Burnham CA, Dukes J, Storch GA. Effectiveness of measures to eradicate Staphylococcus aureus carriage in patients with community-associated skin and soft-tissue infections: a randomized trial. Infect Control Hosp Epidemiol. 2011;32(9):872-80. doi:10.1086/661285 PMCID:PMC3528015 PMID:21828967
35.	Fritz SA, Krauss MJ, Epplin EK, Burnham CA, Garbutt J, Dunne WM, Hunstad DA, Storch GA. The natural history of contemporary Staphylococcus aureus nasal colonization in community children. Pediatr Infect Dis J. 2011;30(4):349-51. doi:10.1097/INF.0b013e3181fe075e PMCID:PMC3077955 PMID:21412205
36.	Fritz SA, Epplin EK, Garbutt J, Storch GA. Skin infection in children colonized with community-associated methicillin-resistant Staphylococcus aureus. J Infect. 2009;59(6):394-401. doi:10.1016/j.jinf.2009.09.001 PMCID:PMC2788074 PMID:19747505
37.	Orscheln RC, Hunstad DA, Fritz SA, Loughman JA, Mitchell K, Storch EK, Gaudreault M, Sellenriek PL, Armstrong JR, Mardis ER, Storch GA. contribution of genetically restricted, methicillin-susceptible strains to the ongoing epidemic of community-acquired Staphylococcus aureus infections. Clin Infect Dis. 2009;49(4):536-42. doi:10.1086/600881 PMCID:PMC2965061 PMID:19589082
38.	Trehan I, Fritz SA. Group B Streptococcus vertebral osteomyelitis-discitis in an immunocompetent adolescent. Pediatr Infect Dis J. 2009;28(6):552-3. doi:10.1097/INF.0b013e3181a4ce6e PMID:19483527
39.	Loughman JA, Fritz SA, Storch GA, Hunstad DA. Virulence gene expression in human community-acquired Staphylococcus aureus infection. J Infect Dis. 2009;199(3):294-301. doi:10.1086/595982 PMCID:PMC2843142 PMID:19115951
40.	Fritz SA, Garbutt J, Elward A, Shannon W, Storch GA. Prevalence of and risk factors for community-acquired methicillin-resistant and methicillin-sensitive staphylococcus aureus colonization in children seen in a practice-based research network. Pediatrics. 2008;121(6):1090-8. doi:10.1542/peds.2007-2104 PMID:18519477
41.	Lutter SA, Currie ML, Mitz LB, Greenbaum LA. Antibiotic resistance patterns in children hospitalized for urinary tract infections. Arch Pediatr Adolesc Med. 2005;159(10):924-8. doi:10.1001/archpedi.159.10.924 PMID:16203936
42.	Lutter SA, Kerschner JE, Chusid MJ. Gradenigo syndrome: a rare but serious complication of otitis media. Pediatr Emerg Care. 2005;21(6):384-6. PMID:15942518
43.	Lutter SA, Glatz JA, Kastner KJ, Taylor SR, Willis E. Filling the cavities between children and oral health. WMJ. 2004;103(5):74-8, 83. PMID:15553570