Projects

The Cooper lab has two main areas of interest: mechanisms of NK cell activation and the genetic basis of pediatric immune dysregulation syndromes.  Current NK cell projects include: 1) metabolic regulation of NK cell activation; 2) metabolic regulation of NK cell anti-viral responses; and 3) enhancing NK cell memory for immunotherapy.  Current projects focused on immune dysregulation include: 1) an in vivo model of STAT3 GOF ; 2) the role of STAT3 in epithelial cell turnover; 3) novel genetic defects in pediatric immune dysregulation syndromes.


Research Opportunities

We are always looking for interested graduate students and post-doctoral fellows to join our research team.  If you are interested in learning more about current projects and opportunities, please e-mail Megan (cooper_m@kids.wustl.edu).


Cooper Lab Accomplishments and News

November 2015: Megan presents the laboratory’s work on STAT3 at the American College of Rheumatology Annual Meeting  
Summer 2015: Annelise and Megan are awarded a grant from the American Association of Immunologists  
June 2015: Tiphanie and Megan have their work highlighted by the CDI  
August 2016: Tiphanie graduates from fellowship and the lab and moves to Baylor to start her own research program!  
September 2016: Molly receives the Shooting Star Award from the Department of Pediatrics for excellence in Research
October 2016, Annelise presents her research at the NK 2016 meeting in Taormina, Italy  
October 2016, Annelise receives a travel award for her research presented at the NK2016 meeting  
September 2017: Annelise awarded an NIH F30 grant for her work on NK cell metabolism  
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