Projects
Vascular Calcification: Mechanism of stimulation by CKD.
Effects of CKD on vascular smooth cell phenotype
Renal Osteodystrophy/Osteoporosis
The effects of of CKD on osteoblast function. Relationship of vascular calcification and bone formation in CKD.
Mechanisms of BMP-7 therapy for vascular calcification
Will BMP-7 treat rather than prevent vascular calcification? (see figure to right) Will BMP-7 increase GFR in severe kidney failure?
New Therapies for Chronic Kidney Disease
Role of selective Prostaglandin E2 receptor agonists/antagonists in diabetic nephropathy Effects of BMP-7 therapy on Renal Osteodystrophy (see figure to right)
Osteoclast Biology: Role of RNA interference in osteoclastogenesis