Rosen Lab

Our lab focuses on the pathogenesis of Klebsiella pneumoniae, an increasingly resistant and versatile organism. One of only three threats deemed “urgent” by the CDC, resistant Klebsiella infections kill half of people afflicted and are only increasing in prevalence. Utilizing mouse models of pneumonia and urinary tract infection (UTI), we are dissecting just how this bacterium causes infection in the host. While our antibiotics may not be successful in killing this pathogen, we are striving to develop methods by which to inhibit virulence of the organism.

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