Misty Good, MD
Misty grew up in a Southern California suburb of Orange County called Brea and was raised by her grandparents. Although she wanted to be a Pediatrician for as long as she can remember, her first interaction of working with kids was at Chuck E. Cheese’s. From starting as a birthday hostess and working up to the privilege of wearing the mouse costume, it is probably this experience that led to her work with mice in the future. While working her way through undergrad, she went on to graduate from the University of Southern California in 2001 and decided she was over the L.A. traffic and needed better weather, so she entered the American University of the Caribbean in St. Maarten. It was over a cadaver in anatomy lab that she met a particular classmate, her amazing and tolerant future husband of 12 years, Zachary Young. They went on to couples match at the University of Illinois School of Medicine in Peoria, where Misty completed her pediatrics residency and chief residency.
During residency, she realized that babies really are the best patient population and she decided to pursue a Neonatal-Perinatal Medicine Fellowship at the University of Pittsburgh. During her clinical training, she cared for many newborns that developed the devastating gastrointestinal disease affecting premature infants called necrotizing enterocolitis (NEC). It was surprising to Misty that although our clinical care of prematurity has increased survival rates particularly of very low birth weight (VLBW) infants, the incidence of NEC and mortality rates remained high. When the time came to choose a lab during fellowship, she wanted to do something to save the babies from NEC. These were lofty goals since she had no prior lab experience and didn’t even know how to pipette yet!
Misty decided that to improve the care of neonates afflicted with NEC, she needed to focus her scientific studies on the molecular mechanisms leading to the dysregulated inflammatory response seen in NEC. Therefore, during her fellowship, she decided to join the laboratory of Dr. David Hackam, a leading surgeon-scientist in the field of NEC research. Maybe it was feeding those cute baby mice every 3 hours or developing a premature piglet model of NEC that convinced her to stay on as research faculty...After completion of her fellowship in 2011, Misty continued her scientific training as junior faculty and was awarded a K08 focused on the anti-inflammatory components of breast milk in protecting against NEC. During these research studies, she began to understand the importance of mucosal immunity in NEC and subsequently did further post-doctoral studies in the lab of Dr. Jay Kolls, a translational mucosal immunologist. After spending two years with Dr. Kolls, Misty joined Washington University in October 2016 and started her own independent laboratory. Her lab seeks to understand the immune cell signaling pathways involved in NEC, to identify infants at risk for NEC development and to develop nutritional strategies to protect against NEC.
When Misty is not resuscitating lab animals, she is taking care of her two English Bulldogs as well as having the privilege of caring for tiny babies in the NICU. Misty also enjoys mentoring students, residents, and fellows, so if you are reading this and want to help save the babies as well, please email her at firstname.lastname@example.org.