Mark J. Manary, M.D.

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Helene B. Roberson Professor of Pediatrics
Researcher, Patient Oriented Research Unit
Emergency Medicine

phone: (314) 454-2341

Research Interests

Dr. Mark Manary's vision is to solve pediatric malnutrition. He was one of the first champions of Ready-to-Use Therapeutic Food (RUTF), a lipid-based food rich in calories and nutrients, to treat uncomplicated severe malnutrition in a child's home, away from hospitals burdened with malnourished children. He conducted the first clinical trial of RUTF in 2001; because of his work, this therapy is now standard of care worldwide. He devotes several months each year to overseeing clinical and translational studies in Malawi, Sierra Lone and Ghana and traveling from village to village treating thousands of malnourished children. The scope of his work includes developing and introducing novel foods, active prevention schemes, and gut microbiota and metabolome in kwashiorkor and marasmus. One of Dr. Manary's current role is a lead scientist in the "Malnutrition Interventions" project for the Peanut & Mycotoxin Innovation Lab, A Feed the Future program.


  • BS, Massachusetts Institute of Technology1977
  • MD, Washington University School of Medicine1982


  • Internship and Residency, St. Louis Children's Hospital1982 - 1985

Licensure and Board Certification

  • 1984 - PresMO, Medical License
  • 1988 - PresAmerican Board of Pediatrics
  • 1989 - PresPediatric Advanced Life Support
  • 1989Pediatric Advanced Life Support - Affiliate Faculty
  • 1989Sexual Assault Forensic Examination (S.A.F.E.) - Provider
  • 1994 - PresAmerican Board of Pediatrics, Subspecialty Pediatric Emergency Medicine

Honors and Awards

  • CIBA Award of Community Service1980
  • St. Louis Pediatric Society Award1982
  • Fulbright Scholar1994 - 1995
  • Academic Humanitarian Physician of the Year, American Association of Medical Colleges2004
  • AOA Member, Washington University Chapter2005
  • Outstanding Graduate Student Mentor Award, Washington University Graduate Student Senate2006
  • Excellence in Pediatrics Award, St. Louis Pediatric Society2007
  • Rose Award for Community Education, St. Louis County Public Schools2007
  • Washington University Distinguished Alumni Faculty Award2007
  • Distinguished Community Service Award, Washington University in St. Louis School of Medicine2012
  • Named as a WHO Expert Advisory on the Management of Malnutrition in Children2012

Selected Publications view all (249)

Publication Co-Authors

Environmental Enteric Dysfunction is Associated with Altered Bile Acid Metabolism. J Pediatr Gastroenterol Nutr. 2016;104(1):191-197. PMID:27322559 
The Association of Serum Choline With Linear Growth Failure in Young Children From Rural Malawi. Am J Clin Nutr. 2016;104(1):191-197. PMID:27281303 
Metabolic Alterations in Children With Environmental Enteric Dysfunction. Sci Rep. 2016;6:28009. PMCID:PMC4904796  PMID:27294788 
Droplet digital PCR Quantifies Host Inflammatory Transcripts in Feces Reliably and Reproducibly Cell Immunol. 2016;303:43-49. PMID:27063479 
Child Stunting is Associated with Low Circulating Essential Amino Acids. EBioMedicine. 2016;6:246-452. PMCID:PMC4856740  PMID:27211567 
Including Whey Protein and Whey Permeate in Ready-To-Use Supplementary Food Improves Recovery Rates in Children With Moderate Acute Malnutrition: A Randomized, Double-Blind Clinical Trial. Am J Clin Nutr. 2016;103(3):926-933. doi:10.3945/ajcn.115.124636  PMID:26864368 
New Insights Into Environmental Enteric Dysfunction. Arch Dis Child. 2016;101(8):741-744. PMID:26933151 
Protein Quality and Growth in Malnourished Children Food Nutr Bull. 2016;37 Suppl 1:S29-S36. PMID:26857118 
Gut Bacteria That Prevent Growth Impairments Transmitted by Microbiota from Malnourished Children. Science. 2016;351(6275). PMCID:PMC4787260  PMID:26912898